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ebi3 Epstein-Barr virus induced 3 [ Danio rerio (zebrafish) ]

Gene ID: 100134974, updated on 12-Sep-2024

Summary

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Official Symbol
ebi3provided by ZNC
Official Full Name
Epstein-Barr virus induced 3provided by ZNC
Primary source
ZFIN:ZDB-GENE-070912-615
See related
Ensembl:ENSDARG00000053620 AllianceGenome:ZFIN:ZDB-GENE-070912-615
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
il-27rb; si:dkey-97a13.4
Summary
Predicted to enable cytokine binding activity; cytokine receptor activity; and peptide hormone binding activity. Predicted to be involved in leptin-mediated signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in liver. Orthologous to human EBI3 (Epstein-Barr virus induced 3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (41936622..41942645, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (42087204..42093227, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene cytokine receptor-like factor 1a Neighboring gene outer dense fiber of sperm tails 3-like 2a Neighboring gene uncharacterized LOC103910102 Neighboring gene helicase with zinc finger 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Metabolism disruption analysis of zebrafish larvae in response to BPA and BPA analogs based on RNA-Seq technique. Qiu W, et al. Ecotoxicol Environ Saf, 2019 Jun 15. PMID 30826544
  2. Evolution of Class I cytokine receptors. Liongue C, et al. BMC Evol Biol, 2007 Jul 18. PMID 17640376, Free PMC Article
  3. Re-evaluating the functional landscape of the cardiovascular system during development. Takada N, et al. Biol Open, 2017 Nov 15. PMID 28982700, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cytokine binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cytokine receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
interleukin-27 subunit beta
Names
Epstein-Barr virus induced gene 3
Il27rbeta
interleukin 27 receptor beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113508.1 → NP_001106980.1  interleukin-27 subunit beta precursor

    See identical proteins and their annotated locations for NP_001106980.1

    Status: PROVISIONAL

    Source sequence(s)
    BN000734
    UniProtKB/TrEMBL
    A8WH81
    Related
    ENSDARP00000070155.4, ENSDART00000075673.5
    Conserved Domains (3) summary
    smart00410
    Location:33 → 96
    IG_like; Immunoglobulin like
    cd00063
    Location:199 → 294
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam13895
    Location:33 → 82
    Ig_2; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    41936622..41942645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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