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PARD6G-AS1 PARD6G antisense RNA 1 [ Homo sapiens (human) ]

Gene ID: 100130522, updated on 10-Oct-2023

Summary

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Official Symbol
PARD6G-AS1provided by HGNC
Official Full Name
PARD6G antisense RNA 1provided by HGNC
Primary source
HGNC:HGNC:44109
See related
Ensembl:ENSG00000267270 AllianceGenome:HGNC:44109
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

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See PARD6G-AS1 in Genome Data Viewer
Location:
18q23
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (80147924..80178432)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (80424381..80454890)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (77905807..77936315)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene RBFA downstream neighbor Neighboring gene solute carrier family 25 member 6 pseudogene 4 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr18:77861530-77862273 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13548 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:77865569-77866070 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:77866897-77867398 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9592 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr18:77876558-77877483 Neighboring gene ADNP homeobox 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9593 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13549 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13550 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9594 Neighboring gene par-6 family cell polarity regulator gamma Neighboring gene uncharacterized LOC124904337 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:77985669-77986170 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:78003535-78004036 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:78004037-78004536 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9595 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13551

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Maternal 5(m)CpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues. de Sá Machado Araújo G, et al. Front Genet, 2018. PMID 29545821, Free PMC Article
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614, Free PMC Article
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Maternal 5mCpG imprints at the PARD6G-AS1 gametic (primary) differentially methylated region (iDMR) are decoupled from parent-of-origin expression effects in multiple human tissues. Despite the constitutive methylation asymmetry observed between the parental alleles at the iDMR, PARD6G-AS1 was expressed biallelically in six tissues: brain amygdala, brain putamen, heart atrial appendage, pituitary, testis, and thyroid.
    Title: Maternal 5(m)CpG Imprints at the PARD6G-AS1 and GCSAML Differentially Methylated Regions Are Decoupled From Parent-of-Origin Expression Effects in Multiple Human Tissues.
  2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
    Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • PARD6G antisense RNA 1 (non-protein coding)

Clone Names

  • FLJ31742, AC139100.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_028339.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC139100, AK056304, BM665099, DA492465
    Related
    ENST00000586421.1

  2. NR_028340.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks two exons and includes two alternate exons, compared to variant 1.
    Source sequence(s)
    DA492465, DB097435, DR003590
    Related
    ENST00000589574.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    80147924..80178432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    80424381..80454890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001145731.1: Suppressed sequence

    Description
    NM_001145731.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.

  2. NM_001145732.1: Suppressed sequence

    Description
    NM_001145732.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.

  3. NM_001145733.1: Suppressed sequence

    Description
    NM_001145733.1: This RefSeq was permanently suppressed because it is now thought that this gene does not encode a protein.
Nucleotide Protein
Heading Accession and Version

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