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st3gal8.L ST3 beta-galactoside alpha-2,3-sialyltransferase 8 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100126621, updated on 4-Nov-2024

Summary

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Official Symbol
st3gal8.L
Official Full Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 8 L homeolog
Primary source
Xenbase:XB-GENE-5928563
Locus tag
XELAEV_18043959mg
See related
EnsemblRapid:ENSXLAG00005032578 AllianceGenome:Xenbase:XB-GENE-5928563
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
st3gal8B; st3gal2.2; st3gal2.2.L
Summary
Predicted to enable beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Predicted to act upstream of or within ganglioside biosynthetic process via lactosylceramide; protein glycosylation; and sialylation. Predicted to be located in Golgi cisterna membrane and extracellular region. Orthologous to human ST3GAL2 (ST3 beta-galactoside alpha-2,3-sialyltransferase 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See st3gal8.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (44267189..44291185)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (33953220..33977359)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene fer-1-like protein 4 Neighboring gene arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Neighboring gene gastrula zinc finger protein XlCGF17.1-like Neighboring gene ERGIC and golgi 3 L homeolog Neighboring gene mitogen-activated protein kinase kinase kinase kinase 4-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate derivative biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ganglioside biosynthetic process via lactosylceramide IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sialylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ST3 beta-galactoside alpha-2,3-sialyltransferase 2, gene 2 L homeolog; ST3 beta-galactoside alpha-2,3-sialyltransferase 8 L homeolog
Names
alpha2,3-sialyltransferase
NP_001104200.1
XP_018089393.1
XP_018089394.1
XP_018089395.1
XP_018089396.1
XP_041431363.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001110730.1 → NP_001104200.1  ST3 beta-galactoside alpha-2,3-sialyltransferase 8 L homeolog

    See identical proteins and their annotated locations for NP_001104200.1

    Status: PROVISIONAL

    Source sequence(s)
    BC153764
    UniProtKB/TrEMBL
    A0A974H2V0, A8E5Y5
    Related
    ENSXLAP00005097599.1, ENSXLAT00005099391.1
    Conserved Domains (1) summary
    pfam00777
    Location:79 → 332
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    44267189..44291185
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018233907.2 → XP_018089396.1  ST3 beta-galactoside alpha-2,3-sialyltransferase 2, gene 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H2V0, A8E5Y5
    Conserved Domains (1) summary
    pfam00777
    Location:79 → 332
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  2. XM_018233906.2 → XP_018089395.1  ST3 beta-galactoside alpha-2,3-sialyltransferase 2, gene 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H2V0, A8E5Y5
    Conserved Domains (1) summary
    pfam00777
    Location:79 → 332
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  3. XM_018233905.2 → XP_018089394.1  ST3 beta-galactoside alpha-2,3-sialyltransferase 2, gene 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H2V0, A8E5Y5
    Conserved Domains (1) summary
    pfam00777
    Location:79 → 332
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  4. XM_041575429.1 → XP_041431363.1  ST3 beta-galactoside alpha-2,3-sialyltransferase 2, gene 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H2V0, A8E5Y5
    Conserved Domains (1) summary
    pfam00777
    Location:79 → 332
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  5. XM_018233904.2 → XP_018089393.1  ST3 beta-galactoside alpha-2,3-sialyltransferase 2, gene 2 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H2V0, A8E5Y5
    Conserved Domains (1) summary
    pfam00777
    Location:79 → 332
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)
Nucleotide Protein Strain
Heading Accession and Version

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