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CYP27A1 cytochrome P450 family 27 subfamily A member 1 [ Sus scrofa (pig) ]

Gene ID: 100126282, updated on 17-Aug-2024

Summary

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Official Symbol
CYP27A1provided by VGNC
Official Full Name
cytochrome P450 family 27 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:103372
See related
Ensembl:ENSSSCG00000016199
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in liver (RPKM 177.6), mixtures (RPKM 68.1) and 3 other tissues See more
Orthologs
human mouse all
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Genomic context

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See CYP27A1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 15 NC_010457.5 (120809886..120852196)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 15 NC_010457.4 (133798107..133831191, complement)

Chromosome 15 - NC_010457.5Genomic Context describing neighboring genes Neighboring gene ring finger protein 25 Neighboring gene serine/threonine kinase 36 Neighboring gene uncharacterized LOC106506368 Neighboring gene tubulin tyrosine ligase like 4 Neighboring gene protein kinase AMP-activated non-catalytic subunit gamma 3 Neighboring gene Wnt family member 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in C21-steroid hormone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to peptide hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cortisol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucocorticoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sterol 26-hydroxylase, mitochondrial
Names
cytochrome P450, family 27, subfamily A, polypeptide 1
NP_001230233.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243304.1 → NP_001230233.1  sterol 26-hydroxylase, mitochondrial

    Status: PROVISIONAL

    Source sequence(s)
    AK232936
    UniProtKB/TrEMBL
    A0A480IQ19, A0A4X1UIJ8, A0A8D1J6B4, I3LAB7
    Related
    ENSSSCP00000020985.3, ENSSSCT00000028116.3
    Conserved Domains (1) summary
    pfam00067
    Location:66 → 523
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010457.5 Reference Sscrofa11.1 Primary Assembly

    Range
    120809886..120852196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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