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CERS6 ceramide synthase 6 [ Sus scrofa (pig) ]

Gene ID: 100126279, updated on 17-Aug-2024

Summary

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Official Symbol
CERS6provided by VGNC
Official Full Name
ceramide synthase 6provided by VGNC
Primary source
VGNC:VGNC:96025
See related
Ensembl:ENSSSCG00000032715
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
LASS6
Expression
Ubiquitous expression in subcutaneous adipose (RPKM 3.9), spleen (RPKM 2.3) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See CERS6 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 15 NC_010457.5 (74927088..75261558)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 15 NC_010457.4 (84094841..84360268)

Chromosome 15 - NC_010457.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102157921 Neighboring gene serine/threonine kinase 39 Neighboring gene ferritin light chain pseudogene Neighboring gene nitric oxide synthase trafficking Neighboring gene SPC25 component of NDC80 kinetochore complex Neighboring gene glucose-6-phosphatase catalytic subunit 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sphingosine N-acyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ceramide synthase 6
Names
LAG1 homolog, ceramide synthase 6
longevity assurance homolog 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010457.5 Reference Sscrofa11.1 Primary Assembly

    Range
    74927088..75261558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021075470.1 → XP_020931129.1  ceramide synthase 6 isoform X2

    UniProtKB/TrEMBL
    A0A480QMY4, A0A4X1VN64, A0A8D0JYW1
    Conserved Domains (2) summary
    cd00086
    Location:80 → 127
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

  2. XM_021075469.1 → XP_020931128.1  ceramide synthase 6 isoform X1

    UniProtKB/TrEMBL
    A0A287BA29, A0A4X1VKE3, A0A8D0SQZ6
    Related
    ENSSSCP00000052932.1, ENSSSCT00000058572.3
    Conserved Domains (2) summary
    cd00086
    Location:80 → 127
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 324
    TRAM_LAG1_CLN8; TLC domain

  3. XM_021075471.1 → XP_020931130.1  ceramide synthase 6 isoform X3

    UniProtKB/TrEMBL
    A0A287B3J6, A0A4X1VLW4, A0A8D0NED6, A0A8D0VT50
    Related
    ENSSSCP00000050982.2, ENSSSCT00000060525.3
    Conserved Domains (2) summary
    cd00086
    Location:80 → 127
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam03798
    Location:131 → 283
    TRAM_LAG1_CLN8; TLC domain
Nucleotide Protein
Heading Accession and Version

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