H19 H19, imprinted maternally expressed transcript (non-protein coding) [Bos taurus (domestic cattle)] - Gene

Summary

Gene symbol: H19
Gene description: H19, imprinted maternally expressed transcript (non-protein coding)
See related: Ensembl:ENSBTAG00000058677
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
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Genomic context

Location:: chromosome: 29

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	29	NC_037356.1 (49510998..49513370)

Chromosome 29 - NC_037356.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:: NC_037356.1 Chromosome 29 Reference ARS-UCD2.0 Primary Assembly

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LncRNA H19 participated in the regulation of the proliferation and apoptosis of male germline stem cells via the IGF-1 signaling pathway
Title: H19 regulates the proliferation of bovine male germline stem cells via IGF-1 signaling pathway.
H19 promoted the differentiation of bovine skeletal muscle satellite cells by suppressing Sirt1/FoxO1.
Title: LncRNA H19 promotes the differentiation of bovine skeletal muscle satellite cells by suppressing Sirt1/FoxO1.
5-aza-dC significantly reduced putative ICR methylation of H19 and increased H19 expression in blastocysts derived from vitrified two-cell embryos.
Title: Effect of 5-aza-2'-deoxycytidine on methylation of the putative imprinted control region of H19 during the in vitro development of vitrified bovine two-cell embryos.
Results confirm that H19 biallelic expression is tightly associated with severe demethylation of paternal H19 DMD in embryos created using somatic cell nuclear transfer.
Title: Expression of variant ribosomal RNA genes in mouse oocytes and preimplantation embryos.
Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle.
Title: Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle.
We obtained majority of bovine H19 gene sequence, identified a single nucleotide polymorphism (SNP) in exon 5 and determined the frequencies of different alleles containing the SNP. Imprinting of cloned animal indistinguishable from controls.
Title: Genomic imprinting of H19 in naturally reproduced and cloned cattle.
Expression profile of the H19 gene in a wide range of fetal cattle organs
Title: The expression profile of the H19 gene in cattle.

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NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.