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Trbc1 T cell receptor beta, constant region 1 [ Mus musculus (house mouse) ]

Gene ID: 100125262, updated on 2-Nov-2024

Summary

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Official Symbol
Trbc1provided by MGI
Official Full Name
T cell receptor beta, constant region 1provided by MGI
Primary source
MGI:MGI:4439726
See related
IMGT/GENE-DB:TRBC1; AllianceGenome:MGI:4439726
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm16802; Tcrb-C1
Summary
Predicted to enable signaling receptor activity. Predicted to be located in plasma membrane. Predicted to be part of alpha-beta T cell receptor complex. Orthologous to several human genes including TRBC1 (T cell receptor beta constant 1) and TRBC2 (T cell receptor beta constant 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See Trbc1 in Genome Data Viewer
Location:
6 19.69 cM; 6 B1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (41515153..41516599)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (41538219..41539665)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene T cell receptor beta chain Neighboring gene STARR-seq mESC enhancer starr_15701 Neighboring gene T cell receptor beta joining 1-6 Neighboring gene T cell receptor beta joining 1-7 Neighboring gene T cell receptor beta joining 2-1 Neighboring gene T cell receptor beta, D region 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genomic organization and sequence of T-cell receptor beta-chain constant- and joining-region genes. Gascoigne NR, et al. Nature, 1984 Aug 2-8. PMID 6336329
  2. Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity. Parenti R, et al. Glia, 2010 Oct. PMID 20578039
  3. Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes. Chou HS, et al. Proc Natl Acad Sci U S A, 1987 Apr. PMID 3470773, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables signaling receptor activity ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of alpha-beta T cell receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of alpha-beta T cell receptor complex ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_006980.1 

    Range
    647425..648871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    41515153..41516599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials