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evl Enah/Vasp-like [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100124792, updated on 4-Nov-2024

Summary

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Official Symbol
evlprovided by Xenbase
Official Full Name
Enah/Vasp-likeprovided by Xenbase
Primary source
Xenbase:XB-GENE-988623
See related
Ensembl:ENSXETG00000002529 AllianceGenome:Xenbase:XB-GENE-988623
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
xevl
Summary
Predicted to enable SH3 domain binding activity and actin binding activity. Predicted to act upstream of or within actin polymerization or depolymerization and protein homotetramerization. Predicted to be located in cell projection; cytoplasm; and stress fiber. Orthologous to human EVL (Enah/Vasp-like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See evl in Genome Data Viewer
Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (96441664..96531153)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (75582176..75670930)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116406877 Neighboring gene echinoderm microtubule associated protein like 2 Neighboring gene delta(4)-desaturase, sphingolipid 2 Neighboring gene YY1 transcription factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
  
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within actin polymerization or depolymerization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein homotetramerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ena/VASP-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001102767.1 → NP_001096237.1  ena/VASP-like protein

    See identical proteins and their annotated locations for NP_001096237.1

    Status: PROVISIONAL

    Source sequence(s)
    BC135364
    UniProtKB/TrEMBL
    A4IH41, F6VSA7
    Conserved Domains (2) summary
    cd01207
    Location:5 → 113
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:361 → 395
    VASP_tetra; VASP tetramerisation domain

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    96441664..96531153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012967870.3 → XP_012823324.1  ena/VASP-like protein isoform X2

    UniProtKB/TrEMBL
    A0A6I8SB88, F6V1N0
    Related
    ENSXETP00000094187.1, ENSXETT00000078099.2
    Conserved Domains (2) summary
    cd01207
    Location:5 → 113
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:675 → 708
    VASP_tetra; VASP tetramerization domain

  2. XM_012967875.3 → XP_012823329.1  ena/VASP-like protein isoform X7

    UniProtKB/TrEMBL
    A0A8J0SS47, F6VSA7
    Conserved Domains (2) summary
    cd01207
    Location:5 → 113
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:382 → 416
    VASP_tetra; VASP tetramerisation domain

  3. XM_012967869.3 → XP_012823323.1  ena/VASP-like protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8REJ7, F6V1N0
    Related
    ENSXETP00000080153.2, ENSXETT00000079000.2
    Conserved Domains (2) summary
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:677 → 710
    VASP_tetra; VASP tetramerization domain

  4. XM_012967871.3 → XP_012823325.1  ena/VASP-like protein isoform X3

    UniProtKB/TrEMBL
    A0A8J0SJY1, F6V1N0
    Conserved Domains (2) summary
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:656 → 689
    VASP_tetra; VASP tetramerization domain

  5. XM_012967874.3 → XP_012823328.1  ena/VASP-like protein isoform X6

    UniProtKB/TrEMBL
    A0A8J0SV51, F6VSA7
    Conserved Domains (2) summary
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:384 → 418
    VASP_tetra; VASP tetramerisation domain

  6. XM_012967876.3 → XP_012823330.1  ena/VASP-like protein isoform X8

    UniProtKB/TrEMBL
    A0A8J0SJY6, F6VSA7
    Related
    ENSXETP00000005384.5, ENSXETT00000005384.5
    Conserved Domains (2) summary
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:363 → 397
    VASP_tetra; VASP tetramerisation domain

  7. XM_012967872.3 → XP_012823326.1  ena/VASP-like protein isoform X4

    UniProtKB/TrEMBL
    A0A8J0SUM3, F6V1N0
    Conserved Domains (1) summary
    pfam08776
    Location:580 → 613
    VASP_tetra; VASP tetramerization domain

  8. XM_012967873.3 → XP_012823327.1  ena/VASP-like protein isoform X5

    UniProtKB/TrEMBL
    A0A8J0STS2, F6V1N0
    Conserved Domains (1) summary
    pfam08776
    Location:560 → 593
    VASP_tetra; VASP tetramerization domain
Nucleotide Protein Strain
Heading Accession and Version

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