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CYP39A1 cytochrome P450 family 39 subfamily A member 1 [ Sus scrofa (pig) ]

Gene ID: 100113410, updated on 10-Oct-2024

Summary

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Official Symbol
CYP39A1provided by VGNC
Official Full Name
cytochrome P450 family 39 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:103375
See related
Ensembl:ENSSSCG00000001718
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in kidney (RPKM 17.4), liver (RPKM 17.2) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See CYP39A1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (41345011..41425854, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (47585570..47666631)

Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase family member 5 Neighboring gene regulator of calcineurin 2 Neighboring gene solute carrier family 25 member 27 Neighboring gene tudor domain containing 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid hydroxylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
24-hydroxycholesterol 7-alpha-hydroxylase
Names
cytochrome P450 39A1
cytochrome P450, family 39, subfamily A, polypeptide 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001101027.2 → NP_001094497.2  24-hydroxycholesterol 7-alpha-hydroxylase isoform 1

    Status: VALIDATED

    Source sequence(s)
    AEMK02000055
    UniProtKB/TrEMBL
    A0A4X1UZW7, F1RQQ2, F1RQQ3
    Related
    ENSSSCP00000001873.4, ENSSSCT00000001920.5

  2. NM_001315744.2 → NP_001302673.2  24-hydroxycholesterol 7-alpha-hydroxylase isoform 2

    Status: VALIDATED

    Source sequence(s)
    AEMK02000055

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

    Range
    41345011..41425854 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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