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SIPA1 signal-induced proliferation-associated 1 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100087074, updated on 30-Apr-2024

Summary

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Gene symbol
SIPA1
Gene description
signal-induced proliferation-associated 1
See related
Ensembl:ENSOANG00000031232
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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See SIPA1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
16
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 3 NC_041730.1 (5352359..5372847)

Chromosome 3 - NC_041730.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase 11 Neighboring gene pecanex 3 Neighboring gene RELA proto-oncogene, NF-kB subunit Neighboring gene lysine acetyltransferase 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041730.1 Chromosome 3 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in epithelial cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of epithelial cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal-induced proliferation-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041730.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    5352359..5372847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029061409.1 → XP_028917242.1  signal-induced proliferation-associated protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A6I8NWE9
    Conserved Domains (2) summary
    pfam00595
    Location:666 → 735
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam02145
    Location:334 → 515
    Rap_GAP; Rap/ran-GAP

  2. XM_029061411.1 → XP_028917244.1  signal-induced proliferation-associated protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A6I8N8N3
    Related
    ENSOANP00000045537.1, ENSOANT00000068623.1
    Conserved Domains (2) summary
    pfam00595
    Location:666 → 735
    PDZ; PDZ domain (Also known as DHR or GLGF)
    pfam02145
    Location:334 → 515
    Rap_GAP; Rap/ran-GAP
Nucleotide Protein
Heading Accession and Version

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