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RAPGEF5 Rap guanine nucleotide exchange factor 5 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100083319, updated on 30-Apr-2024

Summary

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Gene symbol
RAPGEF5
Gene description
Rap guanine nucleotide exchange factor 5
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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See RAPGEF5 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
26
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 8 NC_041735.1 (58738802..58977750)

Chromosome 8 - NC_041735.1Genomic Context describing neighboring genes Neighboring gene interleukin 6 Neighboring gene small nucleolar RNA SNORA7 Neighboring gene dynein heavy chain 11, axonemal Neighboring gene cell division cycle associated 7 like Neighboring gene small nucleolar RNA SNORA7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041735.1 Chromosome 8 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 5
Names
Rap guanine nucleotide exchange factor (GEF) 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041735.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    58738802..58977750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039912832.1 → XP_039768766.1  LOW QUALITY PROTEIN: rap guanine nucleotide exchange factor 5

    UniProtKB/TrEMBL
    A0A6I8P1I5
    Conserved Domains (3) summary
    smart00147
    Location:627 → 867
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    smart00229
    Location:355 → 486
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd04437
    Location:86 → 209
    DEP_Epac; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in Epac-like proteins. Epac (exchange proteins directly activated by cAMP) proteins are GEFs (guanine-nucleotide-exchange factors) for the small GTPases, Rap1 and Rap2. They are directly regulated by ...
Nucleotide Protein
Heading Accession and Version

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