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GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100075502, updated on 30-Apr-2024

Summary

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Gene symbol
GNE
Gene description
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
See related
Ensembl:ENSOANG00000011137
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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See GNE in Genome Data Viewer
Location:
chromosome: X5
Exon count:
19
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) X5 NC_041753.1 (15265051..15387535, complement)

Chromosome X5 - NC_041753.1Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 14 Neighboring gene N-acetylneuraminate synthase Neighboring gene calicin Neighboring gene clathrin light chain A Neighboring gene small nucleolar RNA SNORA7 Neighboring gene uncharacterized LOC120638158 Neighboring gene transfer RNA valine (anticodon AAC) Neighboring gene signal recognition particle 19

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041753.1 Chromosome X5 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylmannosamine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables UDP-N-acetylglucosamine 2-epimerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041753.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    15265051..15387535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039910807.1 → XP_039766741.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X3

    UniProtKB/TrEMBL
    F7DGD3
    Conserved Domains (2) summary
    COG1940
    Location:439 → 677
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:41 → 404
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  2. XM_039910806.1 → XP_039766740.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X2

    UniProtKB/TrEMBL
    F7DGD3
    Conserved Domains (2) summary
    COG1940
    Location:439 → 673
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:41 → 404
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  3. XM_029055890.2 → XP_028911723.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1

    UniProtKB/TrEMBL
    A0A6I8NFE9, A0A6I8P074
    Conserved Domains (2) summary
    COG1940
    Location:439 → 743
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:41 → 404
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  4. XM_039910805.1 → XP_039766739.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1

    UniProtKB/TrEMBL
    A0A6I8NFE9, A0A6I8P074
    Conserved Domains (2) summary
    COG1940
    Location:439 → 743
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:41 → 404
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  5. XM_029055893.2 → XP_028911726.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X4

    UniProtKB/TrEMBL
    A0A6I8P074
    Conserved Domains (2) summary
    COG1940
    Location:409 → 713
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing
Nucleotide Protein
Heading Accession and Version

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