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PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100074273, updated on 30-Apr-2024

Summary

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Gene symbol
PIK3CD
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
See related
Ensembl:ENSOANG00000008173
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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See PIK3CD in Genome Data Viewer
Location:
chromosome: 5
Exon count:
28
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 5 NC_041732.1 (68641117..68696820, complement)

Chromosome 5 - NC_041732.1Genomic Context describing neighboring genes Neighboring gene catenin beta interacting protein 1 Neighboring gene calsyntenin 1 Neighboring gene transmembrane protein 201 Neighboring gene U6atac minor spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041732.1 Chromosome 5 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041732.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    68641117..68696820 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029065769.2 → XP_028921602.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X3

    UniProtKB/TrEMBL
    F7EMH6
    Conserved Domains (5) summary
    cd08693
    Location:296 → 461
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:491 → 672
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:665 → 1030
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:187 → 261
    PI3K_rbd; PI3-kinase family, ras-binding domain

  2. XM_029065768.2 → XP_028921601.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X2

    UniProtKB/TrEMBL
    F7EMH6
    Related
    ENSOANP00000012983.2
    Conserved Domains (5) summary
    cd08693
    Location:314 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:501 → 682
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:675 → 1040
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain
    cl02484
    Location:187 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain

  3. XM_029065762.2 → XP_028921595.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F7EMH6
    Conserved Domains (5) summary
    cd08693
    Location:314 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:509 → 690
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:683 → 1048
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:187 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain

  4. XM_029065763.2 → XP_028921596.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F7EMH6
    Conserved Domains (5) summary
    cd08693
    Location:314 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:509 → 690
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:683 → 1048
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:187 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain

  5. XM_029065765.2 → XP_028921598.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F7EMH6
    Conserved Domains (5) summary
    cd08693
    Location:314 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:509 → 690
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:683 → 1048
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:187 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain

  6. XM_029065764.2 → XP_028921597.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F7EMH6
    Conserved Domains (5) summary
    cd08693
    Location:314 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:509 → 690
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:683 → 1048
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:187 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain

  7. XM_029065766.2 → XP_028921599.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F7EMH6
    Conserved Domains (5) summary
    cd08693
    Location:314 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:509 → 690
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:683 → 1048
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:187 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain

  8. XM_029065767.1 → XP_028921600.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1

    UniProtKB/TrEMBL
    F7EMH6
    Conserved Domains (5) summary
    cd08693
    Location:314 → 479
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    smart00145
    Location:509 → 690
    PI3Ka; Phosphoinositide 3-kinase family, accessory domain (PIK domain)
    cd05174
    Location:683 → 1048
    PI3Kc_IA_delta; Catalytic domain of Class IA Phosphoinositide 3-kinase delta
    pfam00794
    Location:187 → 279
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:31 → 106
    PI3K_p85B; PI3-kinase family, p85-binding domain
Nucleotide Protein
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