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P4HA2 prolyl 4-hydroxylase subunit alpha 2 [ Equus caballus (horse) ]

Gene ID: 100072882, updated on 17-Aug-2024

Summary

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Official Symbol
P4HA2provided by VGNC
Official Full Name
prolyl 4-hydroxylase subunit alpha 2provided by VGNC
Primary source
VGNC:VGNC:21117
See related
Ensembl:ENSECAG00000024817
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See P4HA2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 14 NC_009157.3 (42611828..42673323)

Chromosome 14 - NC_009157.3Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 4 Neighboring gene PDZ and LIM domain 4 Neighboring gene CLIP-associating protein 2-like Neighboring gene uncharacterized LOC100146132 Neighboring gene colony stimulating factor 2 Neighboring gene acyl-CoA synthetase long chain family member 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009157.3 Chromosome 14 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-ascorbic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables procollagen-proline 4-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptidyl-proline hydroxylation to 4-hydroxy-L-proline IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prolyl 4-hydroxylase subunit alpha-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009157.3 Reference EquCab3.0 Primary Assembly

    Range
    42611828..42673323
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023617721.1 → XP_023473489.1  prolyl 4-hydroxylase subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    F6PQW4
    Conserved Domains (2) summary
    smart00702
    Location:346 → 519
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:27 → 113
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  2. XM_023617720.1 → XP_023473488.1  prolyl 4-hydroxylase subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    F6PQW4
    Conserved Domains (2) summary
    smart00702
    Location:346 → 519
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:27 → 113
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  3. XM_023617722.1 → XP_023473490.1  prolyl 4-hydroxylase subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    F6PQW4
    Conserved Domains (2) summary
    smart00702
    Location:346 → 519
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:27 → 113
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  4. XM_023617723.1 → XP_023473491.1  prolyl 4-hydroxylase subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    F6PQW4
    Conserved Domains (2) summary
    smart00702
    Location:346 → 519
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:27 → 113
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  5. XM_023617724.1 → XP_023473492.1  prolyl 4-hydroxylase subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    F6PQW4
    Conserved Domains (2) summary
    smart00702
    Location:346 → 519
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:27 → 113
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  6. XM_023617719.1 → XP_023473487.1  prolyl 4-hydroxylase subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2GYW8, A0A3Q2HRV2, A0A3Q2IBT9
    Related
    ENSECAP00000036019.2, ENSECAT00000057689.2
    Conserved Domains (2) summary
    smart00702
    Location:346 → 513
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:26 → 155
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  7. XM_023617727.1 → XP_023473495.1  prolyl 4-hydroxylase subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    F6PQW4
    Conserved Domains (2) summary
    smart00702
    Location:346 → 539
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:26 → 155
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  8. XM_023617718.1 → XP_023473486.1  prolyl 4-hydroxylase subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    F6PQW4
    Related
    ENSECAP00000022449.3, ENSECAT00000026860.3
    Conserved Domains (2) summary
    smart00702
    Location:346 → 517
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:26 → 155
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region

  9. XM_023617726.1 → XP_023473494.1  prolyl 4-hydroxylase subunit alpha-2 isoform X4

    Conserved Domains (2) summary
    smart00702
    Location:266 → 439
    P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    pfam08336
    Location:26 → 155
    P4Ha_N; Prolyl 4-Hydroxylase alpha-subunit, N-terminal region
Nucleotide Protein
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