U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

PRF1 perforin 1 [ Equus caballus (horse) ]

Gene ID: 100072744, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
PRF1provided by VGNC
Official Full Name
perforin 1provided by VGNC
Primary source
VGNC:VGNC:21831
See related
Ensembl:ENSECAG00000012441
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See PRF1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (59116221..59120880, complement)

Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene nodal growth differentiation factor Neighboring gene phosphatase domain containing paladin 1 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 14 Neighboring gene thymus, brain and testes associated

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_009144.3 Chromosome 1 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pore-forming activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables wide pore channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunological synapse formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
perforin-1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009144.3 Reference EquCab3.0 Primary Assembly

    Range
    59116221..59120880 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001502776.5 → XP_001502826.3  perforin-1

    UniProtKB/TrEMBL
    A0A9L0T3N7, F6SSE0
    Related
    ENSECAP00000010232.2, ENSECAT00000012941.4
    Conserved Domains (2) summary
    cd04032
    Location:388 → 514
    C2_Perforin; C2 domain of Perforin
    smart00457
    Location:167 → 369
    MACPF; membrane-attack complex / perforin
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.