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PTGES2 prostaglandin E synthase 2 [ Equus caballus (horse) ]

Gene ID: 100070332, updated on 17-Aug-2024

Summary

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Official Symbol
PTGES2provided by VGNC
Official Full Name
prostaglandin E synthase 2provided by VGNC
Primary source
VGNC:VGNC:21991
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See PTGES2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 25 NC_009168.3 (32052900..32058090, complement)

Chromosome 25 - NC_009168.3Genomic Context describing neighboring genes Neighboring gene nuclear apoptosis inducing factor 1 Neighboring gene solute carrier family 25 member 25 Neighboring gene lipocalin 2 Neighboring gene bublin coiled coil protein Neighboring gene CDKN1A interacting zinc finger protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009168.3 Chromosome 25 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables prostaglandin-E synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostaglandin E synthase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009168.3 Reference EquCab3.0 Primary Assembly

    Range
    32052900..32058090 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023628980.1 → XP_023484748.1  prostaglandin E synthase 2 isoform X1

    Conserved Domains (2) summary
    cd03197
    Location:219 → 367
    GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2
    cd03040
    Location:96 → 172
    GST_N_mPGES2; GST_N family; microsomal Prostaglandin E synthase Type 2 (mPGES2) subfamily; mPGES2 is a membrane-anchored dimeric protein containing a CXXC motif which catalyzes the isomerization of PGH2 to PGE2. Unlike cytosolic PGE synthase (cPGES) and microsomal ...

  2. XM_023628981.1 → XP_023484749.1  prostaglandin E synthase 2 isoform X2

    Conserved Domains (2) summary
    cd03197
    Location:91 → 239
    GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2
    cl00388
    Location:16 → 44
    Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
Nucleotide Protein
Heading Accession and Version

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