ACAA2 acetyl-CoA acyltransferase 2 [Equus caballus (horse)] - Gene

Summary

Official Symbol: ACAA2provided by VGNC
Official Full Name: acetyl-CoA acyltransferase 2provided by VGNC
Primary source: VGNC:VGNC:50910
See related: Ensembl:ENSECAG00000019394
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Equus caballus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	EquCab3.0 (GCF_002863925.1)	8	NC_009151.3 (71750136..71780769, complement)

Chromosome 8 - NC_009151.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_009151.3 Chromosome 8 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 3-ketoacyl-CoA thiolase, mitochondrial

Names: acetyl-Coenzyme A acyltransferase 2; mitochondrial 3-ketoacyl-CoA thiolase-like protein

NP_001296201.1

EC 2.3.1.16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001309272.1 → NP_001296201.1 3-ketoacyl-CoA thiolase, mitochondrial

See identical proteins and their annotated locations for NP_001296201.1

Status: VALIDATED

Source sequence(s)

JL616308

UniProtKB/TrEMBL

A0A3Q2HGP7, K9K2H8

Related

ENSECAP00000032839.2, ENSECAT00000039200.2

Conserved Domains (2) summary

PRK05790
Location:5 → 395

PRK05790; putative acyltransferase; Provisional

cd00751
Location:8 → 395

thiolase; Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and ...