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HK3 hexokinase 3 [ Equus caballus (horse) ]

Gene ID: 100068725, updated on 17-Aug-2024

Summary

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Official Symbol
HK3provided by VGNC
Official Full Name
hexokinase 3provided by VGNC
Primary source
VGNC:VGNC:18797
See related
Ensembl:ENSECAG00000016508
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See HK3 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 14 NC_009157.3 (4514235..4531049)

Chromosome 14 - NC_009157.3Genomic Context describing neighboring genes Neighboring gene zinc finger protein 346 Neighboring gene ubiquitin interaction motif containing 1 Neighboring gene unc-5 netrin receptor A Neighboring gene uncharacterized LOC111767721

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009157.3 Chromosome 14 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hexokinase-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009157.3 Reference EquCab3.0 Primary Assembly

    Range
    4514235..4531049
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005599204.3 → XP_005599261.1  hexokinase-3 isoform X2

    See identical proteins and their annotated locations for XP_005599261.1

    Conserved Domains (3) summary
    COG5026
    Location:437 → 875
    COG5026; Hexokinase [Carbohydrate transport and metabolism]
    pfam00349
    Location:443 → 634
    Hexokinase_1; Hexokinase
    pfam03727
    Location:640 → 874
    Hexokinase_2; Hexokinase

  2. XM_001498546.5 → XP_001498596.2  hexokinase-3 isoform X1

    See identical proteins and their annotated locations for XP_001498596.2

    UniProtKB/TrEMBL
    F6Z3G9
    Related
    ENSECAP00000014535.1, ENSECAT00000017859.4
    Conserved Domains (2) summary
    pfam00349
    Location:33 → 230
    Hexokinase_1; Hexokinase
    cl27242
    Location:477 → 915
    Hexokinase_2; Hexokinase

  3. XM_023617162.1 → XP_023472930.1  hexokinase-3 isoform X1

    UniProtKB/TrEMBL
    F6Z3G9
    Conserved Domains (2) summary
    pfam00349
    Location:33 → 230
    Hexokinase_1; Hexokinase
    cl27242
    Location:477 → 915
    Hexokinase_2; Hexokinase
Nucleotide Protein
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