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ACO1 aconitase 1 [ Equus caballus (horse) ]

Gene ID: 100067866, updated on 17-Aug-2024

Summary

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Official Symbol
ACO1provided by VGNC
Official Full Name
aconitase 1provided by VGNC
Primary source
VGNC:VGNC:14985
See related
Ensembl:ENSECAG00000014846
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See ACO1 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 23 NC_009166.3 (48869422..48929738)

Chromosome 23 - NC_009166.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111770202 Neighboring gene uncharacterized LOC111770203 Neighboring gene uncharacterized LOC102149554 Neighboring gene RNA sensor RIG-I Neighboring gene TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009166.3 Chromosome 23 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aconitate hydratase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron-responsive element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in citrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytoplasmic aconitate hydratase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009166.3 Reference EquCab3.0 Primary Assembly

    Range
    48869422..48929738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023627458.1 → XP_023483226.1  cytoplasmic aconitate hydratase isoform X2

    UniProtKB/TrEMBL
    A0A3Q2I175, A0A3Q2I8C9
    Related
    ENSECAP00000044391.1, ENSECAT00000056539.2
    Conserved Domains (1) summary
    cl28376
    Location:2 → 889
    AcnA; Aconitase A [Energy production and conversion]

  2. XM_023627457.1 → XP_023483225.1  cytoplasmic aconitate hydratase isoform X1

    UniProtKB/TrEMBL
    A0A9L0RN96, A0A9L0STE1, F6U0H9
    Related
    ENSECAP00000077518.1, ENSECAT00000138460.1
    Conserved Domains (1) summary
    cl28376
    Location:109 → 1006
    AcnA; Aconitase A [Energy production and conversion]

  3. XM_023627459.1 → XP_023483227.1  cytoplasmic aconitate hydratase isoform X2

    UniProtKB/TrEMBL
    A0A3Q2I175, A0A3Q2I8C9
    Related
    ENSECAP00000013327.2, ENSECAT00000016500.3
    Conserved Domains (1) summary
    cl28376
    Location:2 → 889
    AcnA; Aconitase A [Energy production and conversion]
Nucleotide Protein
Heading Accession and Version

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