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STIM2 stromal interaction molecule 2 [ Equus caballus (horse) ]

Gene ID: 100066682, updated on 17-Aug-2024

Summary

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Official Symbol
STIM2provided by VGNC
Official Full Name
stromal interaction molecule 2provided by VGNC
Primary source
VGNC:VGNC:23678
See related
Ensembl:ENSECAG00000009481
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See STIM2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 3 NC_009146.3 (99970856..100141233, complement)

Chromosome 3 - NC_009146.3Genomic Context describing neighboring genes Neighboring gene uracil-DNA glycosylase pseudogene Neighboring gene uncharacterized LOC111772933 Neighboring gene uncharacterized LOC111772934 Neighboring gene TBC1 domain family member 19

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009146.3 Chromosome 3 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of store-operated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in store-operated calcium entry IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
stromal interaction molecule 2
Names
Stromal interaction molecule 2-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009146.3 Reference EquCab3.0 Primary Assembly

    Range
    99970856..100141233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023638268.1 → XP_023494036.1  stromal interaction molecule 2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2I9K1
    Conserved Domains (3) summary
    cd09574
    Location:217 → 290
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    pfam16533
    Location:433 → 501
    SOAR; STIM1 Orai1-activating region
    cl27055
    Location:335 → 425
    MutS_III; MutS domain III

  2. XM_023638267.1 → XP_023494035.1  stromal interaction molecule 2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2I9K1
    Conserved Domains (3) summary
    cd09574
    Location:217 → 290
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    pfam16533
    Location:433 → 509
    SOAR; STIM1 Orai1-activating region
    cl27055
    Location:335 → 500
    MutS_III; MutS domain III

  3. XM_023638266.1 → XP_023494034.1  stromal interaction molecule 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2I9K1
    Related
    ENSECAP00000044149.1, ENSECAT00000035699.2
    Conserved Domains (3) summary
    cd09574
    Location:217 → 290
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    pfam16533
    Location:433 → 530
    SOAR; STIM1 Orai1-activating region
    cl25732
    Location:323 → 524
    SMC_N; RecF/RecN/SMC N terminal domain

  4. XM_023638265.1 → XP_023494033.1  stromal interaction molecule 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2I9K1, F6XSI4
    Related
    ENSECAP00000007502.3, ENSECAT00000009805.4
    Conserved Domains (3) summary
    cd09574
    Location:217 → 290
    SAM_STIM2; SAM domain of STIM2 subfamily proteins
    pfam16533
    Location:433 → 538
    SOAR; STIM1 Orai1-activating region
    cl27055
    Location:335 → 515
    MutS_III; MutS domain III
Nucleotide Protein
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