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SFTPD surfactant protein D [ Equus caballus (horse) ]

Gene ID: 100066341, updated on 17-Aug-2024

Summary

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Official Symbol
SFTPDprovided by VGNC
Official Full Name
surfactant protein Dprovided by VGNC
Primary source
VGNC:VGNC:22906
See related
Ensembl:ENSECAG00000006706
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See SFTPD in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (89805789..89817016, complement)

Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111775042 Neighboring gene mannose binding lectin 1 Neighboring gene olfactory receptor family 2 subfamily AJ member 21, pseudogene Neighboring gene olfactory receptor family 2 subfamily L member 5I, pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009144.3 Chromosome 1 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Serum Surfactant Protein D and Haptoglobin as Potential Biomarkers for Inflammatory Airway Disease in Horses. Bullone M, et al. J Vet Intern Med, 2015 Nov-Dec. PMID 26289543, Free PMC Article
  2. Evaluation of serum amyloid A and surfactant protein D in sera for identification of the clinical condition of horses with bacterial pneumonia. Hobo S, et al. J Vet Med Sci, 2007 Aug. PMID 17827889
  3. Light and electron-microscopic localization of CD9 and surfactant protein A and D in normal lungs of the horse. Bocking T, et al. Can J Vet Res, 2021 Jul. PMID 34248260, Free PMC Article
  4. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Light and electron-microscopic localization of CD9 and surfactant protein A and D in normal lungs of the horse.
    Title: Light and electron-microscopic localization of CD9 and surfactant protein A and D in normal lungs of the horse.
  2. Surfactant protein D and haptoglobin serum concentrations could be a diagnostic aid for equine inflammatory airway disease.
    Title: Serum Surfactant Protein D and Haptoglobin as Potential Biomarkers for Inflammatory Airway Disease in Horses.
  3. The levels of surfactant protein D and serum amyloid A protein in normal horses and those with bacterial pneumonia are reported.
    Title: Evaluation of serum amyloid A and surfactant protein D in sera for identification of the clinical condition of horses with bacterial pneumonia.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

General protein information

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Preferred Names
pulmonary surfactant-associated protein D

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009144.3 Reference EquCab3.0 Primary Assembly

    Range
    89805789..89817016 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001496642.4 → XP_001496692.2  pulmonary surfactant-associated protein D

    See identical proteins and their annotated locations for XP_001496692.2

    UniProtKB/TrEMBL
    A0A9L0SW71, F7DJE3
    Related
    ENSECAP00000080267.1, ENSECAT00000102037.1
    Conserved Domains (3) summary
    cd03591
    Location:262 → 375
    CLECT_collectin_like; C-type lectin-like domain (CTLD) of the type found in human collectins including lung surfactant proteins A and D, mannose- or mannan binding lectin (MBL), and CL-L1 (collectin liver 1)
    pfam01391
    Location:130 → 189
    Collagen; Collagen triple helix repeat (20 copies)
    pfam09006
    Location:224 → 269
    Surfac_D-trimer; Lung surfactant protein D coiled-coil trimerization
Nucleotide Protein
Heading Accession and Version

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