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GRK5 G protein-coupled receptor kinase 5 [ Equus caballus (horse) ]

Gene ID: 100065919, updated on 17-Aug-2024

Summary

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Official Symbol
GRK5provided by VGNC
Official Full Name
G protein-coupled receptor kinase 5provided by VGNC
Primary source
VGNC:VGNC:51528
See related
Ensembl:ENSECAG00000023764
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See GRK5 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (13156199..13370973, complement)

Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111772977 Neighboring gene regulator of G protein signaling 10 Neighboring gene high affinity immunoglobulin epsilon receptor subunit gamma Neighboring gene uncharacterized LOC111772984 Neighboring gene peroxiredoxin 3 Neighboring gene sideroflexin 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009144.3 Chromosome 1 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled receptor kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
G protein-coupled receptor kinase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009144.3 Reference EquCab3.0 Primary Assembly

    Range
    13156199..13370973 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023638461.1 → XP_023494229.1  G protein-coupled receptor kinase 5 isoform X4

    UniProtKB/TrEMBL
    A0A9L0TH12
    Conserved Domains (2) summary
    cd05632
    Location:236 → 548
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:53 → 228
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  2. XM_023638436.1 → XP_023494204.1  G protein-coupled receptor kinase 5 isoform X1

    UniProtKB/TrEMBL
    A0A9L0TH12
    Conserved Domains (2) summary
    cd05632
    Location:260 → 572
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:77 → 252
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  3. XM_023638470.1 → XP_023494238.1  G protein-coupled receptor kinase 5 isoform X5

    UniProtKB/TrEMBL
    A0A3Q2H1X0, A0A9L0TH12
    Related
    ENSECAP00000027524.2, ENSECAT00000046001.2
    Conserved Domains (2) summary
    cd05632
    Location:207 → 519
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:77 → 199
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  4. XM_023638452.1 → XP_023494220.1  G protein-coupled receptor kinase 5 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2H629
    Related
    ENSECAP00000029280.2, ENSECAT00000039565.2
    Conserved Domains (2) summary
    cd05632
    Location:237 → 549
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:54 → 229
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  5. XM_023638444.1 → XP_023494212.1  G protein-coupled receptor kinase 5 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2HXP2
    Conserved Domains (2) summary
    cd05632
    Location:241 → 553
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:58 → 233
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  6. XM_023638487.1 → XP_023494255.1  G protein-coupled receptor kinase 5 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2HEN4
    Related
    ENSECAP00000089514.1, ENSECAT00000122503.1
    Conserved Domains (2) summary
    cd05632
    Location:78 → 390
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:1 → 70
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  7. XM_023638480.1 → XP_023494248.1  G protein-coupled receptor kinase 5 isoform X7

    UniProtKB/TrEMBL
    A0A3Q2HEN4
    Conserved Domains (2) summary
    cd05632
    Location:131 → 443
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:62 → 123
    RGS; Regulator of G protein signaling (RGS) domain superfamily

  8. XM_023638474.1 → XP_023494242.1  G protein-coupled receptor kinase 5 isoform X6

    UniProtKB/TrEMBL
    A0A3Q2HEN4
    Related
    ENSECAP00000032052.2, ENSECAT00000039682.3
    Conserved Domains (2) summary
    cd05632
    Location:193 → 505
    STKc_GRK5; Catalytic domain of the Serine/Threonine Kinase, G protein-coupled Receptor Kinase 5
    cl02565
    Location:10 → 185
    RGS; Regulator of G protein signaling (RGS) domain superfamily
Nucleotide Protein
Heading Accession and Version

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