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HEXA hexosaminidase subunit alpha [ Equus caballus (horse) ]

Gene ID: 100063584, updated on 17-Aug-2024

Summary

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Official Symbol
HEXAprovided by VGNC
Official Full Name
hexosaminidase subunit alphaprovided by VGNC
Primary source
VGNC:VGNC:111930
See related
Ensembl:ENSECAG00000011466
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See HEXA in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 1 NC_009144.3 (122110245..122136977)

Chromosome 1 - NC_009144.3Genomic Context describing neighboring genes Neighboring gene transmembrane protein 202 Neighboring gene NADH dehydrogenase (ubiquinone) complex I, assembly factor 6-like Neighboring gene CUGBP Elav-like family member 6 Neighboring gene poly(ADP-ribose) polymerase family member 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009144.3 Chromosome 1 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-N-acetylhexosaminidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ganglioside catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycosaminoglycan metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-hexosaminidase subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009144.3 Reference EquCab3.0 Primary Assembly

    Range
    122110245..122136977
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001494311.5 → XP_001494361.1  beta-hexosaminidase subunit alpha

    UniProtKB/TrEMBL
    A0A5F5PIT2, A0A5F5PPC4
    Related
    ENSECAP00000050535.2, ENSECAT00000066705.2
    Conserved Domains (2) summary
    cd06562
    Location:167 → 511
    GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...
    pfam14845
    Location:24 → 145
    Glycohydro_20b2; beta-acetyl hexosaminidase like
Nucleotide Protein
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Gene LinkOut

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Molecular Biology Databases
Research Materials