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NR3C1 nuclear receptor subfamily 3 group C member 1 [ Equus caballus (horse) ]

Gene ID: 100061217, updated on 17-Aug-2024

Summary

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Official Symbol
NR3C1provided by VGNC
Official Full Name
nuclear receptor subfamily 3 group C member 1provided by VGNC
Primary source
VGNC:VGNC:20869
See related
Ensembl:ENSECAG00000009473
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
GR
Orthologs
human mouse all
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Genomic context

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See NR3C1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 14 NC_009157.3 (33130560..33242717)

Chromosome 14 - NC_009157.3Genomic Context describing neighboring genes Neighboring gene potassium channel tetramerization domain containing 16 Neighboring gene Yip1 domain family member 5 Neighboring gene Rho GTPase activating protein 26 Neighboring gene microRNA mir-9162 Neighboring gene uncharacterized LOC111767776 Neighboring gene fibroblast growth factor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009157.3 Chromosome 14 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estrogen response element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear glucocorticoid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucocorticoid mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear receptor-mediated glucocorticoid signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glucocorticoid receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195191.2 → NP_001182120.1  glucocorticoid receptor

    See identical proteins and their annotated locations for NP_001182120.1

    Status: VALIDATED

    Source sequence(s)
    PJAA01000015
    UniProtKB/TrEMBL
    F6WPN5
    Related
    ENSECAP00000073027.1, ENSECAT00000123098.1
    Conserved Domains (3) summary
    cd07076
    Location:529 → 775
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:415 → 492
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009157.3 Reference EquCab3.0 Primary Assembly

    Range
    33130560..33242717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023616905.1 → XP_023472673.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    F6WPN5
    Conserved Domains (3) summary
    cd07076
    Location:530 → 776
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:415 → 493
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor

  2. XM_023616904.1 → XP_023472672.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    F6WPN5
    Related
    ENSECAP00000007606.3, ENSECAT00000009918.4
    Conserved Domains (3) summary
    cd07076
    Location:530 → 776
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:415 → 493
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor

  3. XM_023616906.1 → XP_023472674.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    F6WPN5
    Conserved Domains (3) summary
    cd07076
    Location:530 → 776
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:415 → 493
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor

  4. XM_023616903.1 → XP_023472671.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    F6WPN5
    Conserved Domains (3) summary
    cd07076
    Location:530 → 776
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:415 → 493
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor

  5. XM_023616910.1 → XP_023472678.1  glucocorticoid receptor isoform X3

    UniProtKB/TrEMBL
    A0A9L0SG91
    Conserved Domains (3) summary
    cd07172
    Location:415 → 493
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor
    cl11397
    Location:530 → 673
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators

  6. XM_023616908.1 → XP_023472676.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    F6WPN5
    Conserved Domains (3) summary
    cd07076
    Location:530 → 776
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:415 → 493
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor

  7. XM_023616907.1 → XP_023472675.1  glucocorticoid receptor isoform X1

    UniProtKB/TrEMBL
    F6WPN5
    Conserved Domains (3) summary
    cd07076
    Location:530 → 776
    NR_LBD_GR; Ligand binding domain of the glucocorticoid receptor, a member of the nuclear receptor superfamily
    cd07172
    Location:415 → 493
    NR_DBD_GR_PR; DNA-binding domain of glucocorticoid receptor (GR) is composed of two C4-type zinc fingers
    pfam02155
    Location:27 → 400
    GCR; Glucocorticoid receptor
Nucleotide Protein Strain
Heading Accession and Version

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