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CAPN8 calpain 8 [ Equus caballus (horse) ]

Gene ID: 100055093, updated on 17-Aug-2024

Summary

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Official Symbol
CAPN8provided by VGNC
Official Full Name
calpain 8provided by VGNC
Primary source
VGNC:VGNC:58136
See related
Ensembl:ENSECAG00000018301
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See CAPN8 in Genome Data Viewer
Location:
chromosome: 30
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 30 NC_009173.3 (9713140..9775883)

Chromosome 30 - NC_009173.3Genomic Context describing neighboring genes Neighboring gene tumor protein p53 binding protein 2 Neighboring gene microRNA mir-9126 Neighboring gene U6 spliceosomal RNA Neighboring gene calpain 2 Neighboring gene coiled-coil domain containing 185 Neighboring gene sushi domain containing 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009173.3 Chromosome 30 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009173.3 Reference EquCab3.0 Primary Assembly

    Range
    9713140..9775883
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023632811.1 → XP_023488579.1  calpain-8 isoform X1

    UniProtKB/TrEMBL
    F7BLU8
    Related
    ENSECAP00000016851.3, ENSECAT00000020526.4
    Conserved Domains (3) summary
    pfam00648
    Location:46 → 342
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:363 → 509
    Calpain_III; Calpain large subunit, domain III
    cd16191
    Location:536 → 703
    EFh_PEF_CAPN8; Penta-EF hand, calcium binding motifs, found in calpain-8 (CAPN8)

  2. XM_023632812.1 → XP_023488580.1  calpain-8 isoform X2

    UniProtKB/TrEMBL
    F7BLU8
    Conserved Domains (4) summary
    pfam00648
    Location:46 → 342
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:363 → 509
    Calpain_III; Calpain large subunit, domain III
    cd15897
    Location:556 → 585
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:524 → 680
    EFh_PEF; The penta-EF hand (PEF) family
Nucleotide Protein
Heading Accession and Version

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