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PLCD1 phospholipase C delta 1 [ Equus caballus (horse) ]

Gene ID: 100054233, updated on 17-Aug-2024

Summary

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Official Symbol
PLCD1provided by VGNC
Official Full Name
phospholipase C delta 1provided by VGNC
Primary source
VGNC:VGNC:21539
See related
Ensembl:ENSECAG00000023703
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See PLCD1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 16 NC_009159.3 (48788478..48810257)

Chromosome 16 - NC_009159.3Genomic Context describing neighboring genes Neighboring gene acetyl-CoA acyltransferase 1 Neighboring gene DLEC1 cilia and flagella associated protein Neighboring gene uncharacterized LOC102150170 Neighboring gene villin like Neighboring gene CTD small phosphatase like Neighboring gene microRNA mir-26a-2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009159.3 Chromosome 16 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009159.3 Reference EquCab3.0 Primary Assembly

    Range
    48788478..48810257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023620741.1 → XP_023476509.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X3

    UniProtKB/TrEMBL
    A0A9L0SZX3, F6XW20
    Related
    ENSECAP00000021399.3, ENSECAT00000025706.3
    Conserved Domains (4) summary
    cd00275
    Location:628 → 754
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:295 → 595
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:22 → 139
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:144 → 283
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)

  2. XM_023620740.1 → XP_023476508.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X2

    UniProtKB/TrEMBL
    A0A9L0TSM6
    Related
    ENSECAP00000082851.1, ENSECAT00000103709.1
    Conserved Domains (4) summary
    cd00275
    Location:570 → 696
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:237 → 537
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd16217
    Location:86 → 225
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)
    cl17171
    Location:1 → 81
    PH-like; Pleckstrin homology-like domain

  3. XM_001489014.5 → XP_001489064.3  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2H2Z5, A0A3Q2HRP7
    Related
    ENSECAP00000036753.2, ENSECAT00000056970.3
    Conserved Domains (4) summary
    cd00275
    Location:728 → 854
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08593
    Location:395 → 695
    PI-PLCc_delta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-delta
    cd13363
    Location:122 → 239
    PH_PLC_delta; Phospholipase C-delta (PLC-delta) pleckstrin homology (PH) domain
    cd16217
    Location:244 → 383
    EFh_PI-PLCdelta1; EF-hand motif found in phosphoinositide phospholipase C delta 1 (PI-PLC-delta1)
Nucleotide Protein
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