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SFTPC surfactant protein C [ Equus caballus (horse) ]

Gene ID: 100053773, updated on 17-Aug-2024

Summary

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Official Symbol
SFTPCprovided by VGNC
Official Full Name
surfactant protein Cprovided by VGNC
Primary source
VGNC:VGNC:22905
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See SFTPC in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 2 NC_009145.3 (51298555..51301347)

Chromosome 2 - NC_009145.3Genomic Context describing neighboring genes Neighboring gene leucine rich repeat LGI family member 3 Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene bone morphogenetic protein 1 Neighboring gene phytanoyl-CoA 2-hydroxylase interacting protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009145.3 Chromosome 2 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in respiratory gaseous exchange by respiratory system IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in alveolar lamellar body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
surfactant protein C
Names
pulmonary surfactant associated protein C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009145.3 Reference EquCab3.0 Primary Assembly

    Range
    51298555..51301347
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014737743.2 → XP_014593229.1  surfactant protein C isoform X1

    Conserved Domains (3) summary
    smart00019
    Location:1 → 219
    SF_P; Pulmonary surfactant proteins
    smart01039
    Location:94 → 219
    BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer
    pfam08999
    Location:1 → 93
    SP_C-Propep; Surfactant protein C, N terminal propeptide

  2. XM_001491075.5 → XP_001491125.3  surfactant protein C isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ICV2
    Conserved Domains (3) summary
    smart00019
    Location:1 → 190
    SF_P; Pulmonary surfactant proteins
    smart01039
    Location:94 → 190
    BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer
    pfam08999
    Location:1 → 93
    SP_C-Propep; Surfactant protein C, N terminal propeptide
Nucleotide Protein
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