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ASB3 ankyrin repeat and SOCS box containing 3 [ Equus caballus (horse) ]

Gene ID: 100052747, updated on 15-Aug-2024

Summary

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Gene symbol
ASB3
Gene description
ankyrin repeat and SOCS box containing 3
See related
Ensembl:ENSECAG00000022145
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See ASB3 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 15 NC_009158.3 (47295797..47404225)

Chromosome 15 - NC_009158.3Genomic Context describing neighboring genes Neighboring gene proteasome activator subunit 4 Neighboring gene G protein-coupled receptor 75 Neighboring gene endoplasmic reticulum lectin 1 Neighboring gene ChaC glutathione specific gamma-glutamylcyclotransferase 2 Neighboring gene uncharacterized LOC106781739 Neighboring gene uncharacterized LOC111768214

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009158.3 Chromosome 15 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ankyrin repeat and SOCS box protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205056.1 → NP_001191985.1  ankyrin repeat and SOCS box protein 3

    See identical proteins and their annotated locations for NP_001191985.1

    Status: PROVISIONAL

    Source sequence(s)
    PJAA01000016
    UniProtKB/TrEMBL
    A0A3Q2I1E5, A0A5F5PM92
    Related
    ENSECAP00000049785.2, ENSECAT00000069113.2
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:458 → 508
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009158.3 Reference EquCab3.0 Primary Assembly

    Range
    47295797..47404225
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023618407.1 → XP_023474175.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:476 → 526
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_023618411.1 → XP_023474179.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:476 → 526
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_023618412.1 → XP_023474180.1  ankyrin repeat and SOCS box protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2I1E5, A0A5F5PM92
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:458 → 508
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_023618403.1 → XP_023474171.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:476 → 526
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_023618402.1 → XP_023474170.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    F6X8R1
    Related
    ENSECAP00000019570.3, ENSECAT00000023617.4
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:476 → 526
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_023618408.1 → XP_023474176.1  ankyrin repeat and SOCS box protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2I1E5, A0A5F5PM92
    Related
    ENSECAP00000039533.1, ENSECAT00000049956.2
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:458 → 508
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_023618409.1 → XP_023474177.1  ankyrin repeat and SOCS box protein 3 isoform X3

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (3) summary
    cd00204
    Location:93 → 214
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:423 → 473
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:93 → 123
    ANK; ANK repeat [structural motif]

  8. XM_023618410.1 → XP_023474178.1  ankyrin repeat and SOCS box protein 3 isoform X3

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (3) summary
    cd00204
    Location:93 → 214
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:423 → 473
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:93 → 123
    ANK; ANK repeat [structural motif]

  9. XM_023618405.1 → XP_023474173.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:476 → 526
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  10. XM_023618404.1 → XP_023474172.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:476 → 526
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)

  11. XM_023618406.1 → XP_023474174.1  ankyrin repeat and SOCS box protein 3 isoform X1

    UniProtKB/TrEMBL
    F6X8R1
    Conserved Domains (4) summary
    cd00204
    Location:78 → 199
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd03722
    Location:476 → 526
    SOCS_ASB3; SOCS (suppressors of cytokine signaling) box of ASB3-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. ABS3 has been shown to be negative regulator of TNF-R2-mediated cellular responses to TNF-alpha ...
    sd00045
    Location:146 → 176
    ANK; ANK repeat [structural motif]
    cl26073
    Location:161 → 404
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
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