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DBT dihydrolipoamide branched chain transacylase E2 [ Equus caballus (horse) ]

Gene ID: 100050317, updated on 17-Aug-2024

Summary

Official Symbol
DBTprovided by VGNC
Official Full Name
dihydrolipoamide branched chain transacylase E2provided by VGNC
Primary source
VGNC:VGNC:17022
See related
Ensembl:ENSECAG00000021626
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
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Genomic context

See DBT in Genome Data Viewer
Location:
chromosome: 5
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 5 NC_009148.3 (62609677..62652213)

Chromosome 5 - NC_009148.3Genomic Context describing neighboring genes Neighboring gene cell division cycle 14A Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene leucine rich repeat containing 39 Neighboring gene tRNA methyltransferase 13 homolog Neighboring gene SAS-6 centriolar assembly protein

Genomic regions, transcripts, and products

Genomic Sequence:
NC_009148.3 Chromosome 5 Reference EquCab3.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables lipoic acid binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009148.3 Reference EquCab3.0 Primary Assembly

    Range
    62609677..62652213
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001488612.6XP_001488662.2  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A3Q2I278
    Related
    ENSECAP00000041189.3, ENSECAT00000030945.3
    Conserved Domains (4) summary
    cd06849
    Location:65138
    lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...
    PLN02528
    Location:67482
    PLN02528; 2-oxoisovalerate dehydrogenase E2 component
    pfam00198
    Location:267479
    2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
    pfam02817
    Location:172205
    E3_binding; e3 binding domain
  2. XM_023641557.1XP_023497325.1  lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A3Q2I278
    Conserved Domains (1) summary
    cl27351
    Location:67456
    E3_binding; e3 binding domain