SHMT2 serine hydroxymethyltransferase 2 [Equus caballus (horse)] - Gene

Summary

Official Symbol: SHMT2provided by VGNC
Official Full Name: serine hydroxymethyltransferase 2provided by VGNC
Primary source: VGNC:VGNC:22965
See related: Ensembl:ENSECAG00000021295
Gene type: protein coding
RefSeq status: MODEL
Organism: Equus caballus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs: human mouse all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	EquCab3.0 (GCF_002863925.1)	6	NC_009149.3 (75820466..75825517)

Chromosome 6 - NC_009149.3 Genomic Context describing neighboring genes

Genomic Sequence:: NC_009149.3 Chromosome 6 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables cobalt ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables glycine hydroxymethyltransferase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info	PubMed
enables serine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in L-serine catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in folic acid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glycine biosynthetic process from serine	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of oxidative phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to type I interferon	IEA Inferred from Electronic Annotation more info	PubMed
involved_in tetrahydrofolate interconversion	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of BRISC complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info	PubMed

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The following sections contain reference sequences that belong to a specific genome build. Explain