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INSIG2 insulin induced gene 2 [ Equus caballus (horse) ]

Gene ID: 100049957, updated on 17-Aug-2024

Summary

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Official Symbol
INSIG2provided by VGNC
Official Full Name
insulin induced gene 2provided by VGNC
Primary source
VGNC:VGNC:19081
See related
Ensembl:ENSECAG00000006707
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See INSIG2 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 18 NC_009161.3 (12794617..12819716, complement)

Chromosome 18 - NC_009161.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111768882 Neighboring gene uncharacterized LOC111768883 Neighboring gene uncharacterized LOC102150381 Neighboring gene uncharacterized LOC102150544 Neighboring gene coiled-coil domain containing 93 Neighboring gene 5-hydroxytryptamine receptor 5B-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009161.3 Chromosome 18 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in SREBP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in SREBP-SCAP complex retention in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of SREBP-SCAP-Insig complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-induced gene 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009161.3 Reference EquCab3.0 Primary Assembly

    Range
    12794617..12819716 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001488083.5 → XP_001488133.1  insulin-induced gene 2 protein

    See identical proteins and their annotated locations for XP_001488133.1

    UniProtKB/TrEMBL
    F6V608
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  2. XM_014732428.2 → XP_014587914.1  insulin-induced gene 2 protein

    UniProtKB/TrEMBL
    F6V608
    Related
    ENSECAP00000004963.1, ENSECAT00000006893.4
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  3. XM_014732432.2 → XP_014587918.1  insulin-induced gene 2 protein

    UniProtKB/TrEMBL
    F6V608
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  4. XM_014732433.2 → XP_014587919.1  insulin-induced gene 2 protein

    UniProtKB/TrEMBL
    F6V608
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  5. XM_014732427.2 → XP_014587913.1  insulin-induced gene 2 protein

    UniProtKB/TrEMBL
    F6V608
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  6. XM_005601452.3 → XP_005601509.1  insulin-induced gene 2 protein

    See identical proteins and their annotated locations for XP_005601509.1

    UniProtKB/TrEMBL
    F6V608
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)

  7. XM_014732429.2 → XP_014587915.1  insulin-induced gene 2 protein

    UniProtKB/TrEMBL
    F6V608
    Conserved Domains (1) summary
    pfam07281
    Location:31 → 211
    INSIG; Insulin-induced protein (INSIG)
Nucleotide Protein
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