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sbds.S SBDS ribosome assembly guanine nucleotide exchange factor S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100049749, updated on 4-Nov-2024

Summary

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Official Symbol
sbds.S
Official Full Name
SBDS ribosome assembly guanine nucleotide exchange factor S homeolog
Primary source
Xenbase:XB-GENE-1003512
Locus tag
XELAEV_18015375mg
See related
EnsemblRapid:ENSXLAG00005003747 AllianceGenome:Xenbase:XB-GENE-1003512
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sbds
Summary
Predicted to enable ribosome binding activity. Predicted to act upstream of or within cytosolic ribosome assembly and hematopoietic progenitor cell differentiation. Predicted to be located in spindle pole. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome and aplastic anemia. Orthologous to human SBDS (SBDS ribosome maturation factor). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sbds.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (89890578..89897575, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (80883921..80890966, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene nipsnap homolog 2 S homeolog Neighboring gene uncharacterized LOC121400632 Neighboring gene tRNA-yW synthesizing protein 1 homolog S homeolog Neighboring gene uncharacterized LOC108709649

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ribosome binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cytosolic ribosome assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cytosolic ribosome assembly ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within hematopoietic progenitor cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
ribosome maturation protein SBDS
Names
SBDS, ribosome maturation factorS homeolog
Shwachman-Bodian-Diamond syndrome S homeolog
shwachman-Bodian-Diamond syndrome protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098689.1 → NP_001092159.1  ribosome maturation protein SBDS

    See identical proteins and their annotated locations for NP_001092159.1

    Status: PROVISIONAL

    Source sequence(s)
    BC141736
    UniProtKB/Swiss-Prot
    A5D8M6
    UniProtKB/TrEMBL
    A0A974DHW0
    Related
    ENSXLAP00005011175.1, ENSXLAT00005011350.1
    Conserved Domains (3) summary
    COG1500
    Location:9 → 241
    Sdo1; Ribosome maturation protein Sdo1 [Translation, ribosomal structure and biogenesis]
    pfam01172
    Location:17 → 98
    SBDS; Shwachman-Bodian-Diamond syndrome (SBDS) protein
    pfam09377
    Location:107 → 224
    SBDS_C; SBDS protein C-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    89890578..89897575 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A5D8M6.1 GenPept UniProtKB/Swiss-Prot:A5D8M6

Gene LinkOut

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