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alg6.L ALG6, alpha-1,3-glucosyltransferase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100049135, updated on 4-Nov-2024

Summary

Official Symbol
alg6.L
Official Full Name
ALG6, alpha-1,3-glucosyltransferase L homeolog
Primary source
Xenbase:XB-GENE-998193
Locus tag
XELAEV_18022997mg
See related
EnsemblRapid:ENSXLAG00005012251 AllianceGenome:Xenbase:XB-GENE-998193
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
alg6
Summary
Predicted to enable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to act upstream of or within protein N-linked glycosylation. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Orthologous to human ALG6 (ALG6 alpha-1,3-glucosyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See alg6.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (79820995..79846519, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (74526886..74552566, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 7 L homeolog Neighboring gene centromere protein R Neighboring gene forkhead box D3 L homeolog Neighboring gene autophagy related 4C, cysteine peptidase L homeolog

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within protein N-linked glycosylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ALG6, alpha-1,3-glucosyltransferase L homeolog
Names
asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097964.1NP_001091433.1  ALG6, alpha-1,3-glucosyltransferase L homeolog precursor

    See identical proteins and their annotated locations for NP_001091433.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133798
    UniProtKB/TrEMBL
    A0A974D654, A4FVF3
    Related
    ENSXLAP00005035902.1, ENSXLAT00005036802.1
    Conserved Domains (1) summary
    pfam03155
    Location:32487
    Alg6_Alg8; ALG6, ALG8 glycosyltransferase family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    79820995..79846519 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018256329.2XP_018111818.1  ALG6, alpha-1,3-glucosyltransferase L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0V291, A0A974D654
    Related
    ENSXLAP00005035910.1, ENSXLAT00005036810.1
  2. XM_018256328.2XP_018111817.1  ALG6, alpha-1,3-glucosyltransferase L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0UYM0, A0A974D654
  3. XM_018256327.2XP_018111816.1  ALG6, alpha-1,3-glucosyltransferase L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0UXE7, A0A974D654
    Related
    ENSXLAP00005035908.1, ENSXLAT00005036808.1
  4. XM_018256330.1XP_018111819.1  ALG6, alpha-1,3-glucosyltransferase L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J0UYD3, A0A974D654
    Related
    ENSXLAP00005035898.1, ENSXLAT00005036798.1
  5. XM_018256331.2XP_018111820.1  ALG6, alpha-1,3-glucosyltransferase L homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J0USB8, A0A974D654
    Related
    ENSXLAP00005035918.1, ENSXLAT00005036818.1