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dnajc19.L DnaJ heat shock protein family (Hsp40) member C19 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100049122, updated on 4-Nov-2024

Summary

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Official Symbol
dnajc19.L
Official Full Name
DnaJ heat shock protein family (Hsp40) member C19 L homeolog
Primary source
Xenbase:XB-GENE-5842970
Locus tag
XELAEV_18030615mg
See related
EnsemblRapid:ENSXLAG00005030038 AllianceGenome:Xenbase:XB-GENE-5842970
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
dnajc19
Summary
Predicted to enable ATPase activator activity. Predicted to act upstream of or within protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of PAM complex, Tim23 associated import motor. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 5. Orthologous to human DNAJC19 (DnaJ heat shock protein family (Hsp40) member C19). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See dnajc19.L in Genome Data Viewer
Location:
chromosome: 6L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6L NC_054381.1 (10172421..10180253, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6L NC_030734.1 (7714504..7722338, complement)

Chromosome 6L - NC_054381.1Genomic Context describing neighboring genes Neighboring gene MINDY lysine 48 deubiquitinase 4 L homeolog Neighboring gene selenoprotein N L homeolog Neighboring gene proteasome maturation protein L homeolog Neighboring gene corticotropin releasing hormone receptor 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATPase activator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein import into mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of PAM complex, Tim23 associated import motor IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DnaJ heat shock protein family (Hsp40) member C19 L homeolog
Names
DnaJ (Hsp40) homolog, subfamily C, member 19

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097955.1 → NP_001091424.1  DnaJ heat shock protein family (Hsp40) member C19 L homeolog

    See identical proteins and their annotated locations for NP_001091424.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133813
    UniProtKB/TrEMBL
    A0A974CMJ1, A3KNF5
    Related
    ENSXLAP00005089826.1, ENSXLAT00005091503.1
    Conserved Domains (1) summary
    cl02542
    Location:52 → 109
    DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054381.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    10172421..10180253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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