Tcf24 transcription factor 24 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tcf24provided by MGI
Official Full Name: transcription factor 24provided by MGI
Primary source: MGI:MGI:3780500
See related: Ensembl:ENSMUSG00000099032 AllianceGenome:MGI:3780500
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm2330; Gm10567
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Orthologous to human TCF24 (transcription factor 24). [provided by Alliance of Genome Resources, Oct 2024]
Expression: Biased expression in adrenal adult (RPKM 7.3), placenta adult (RPKM 3.4) and 9 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 A2; 1 2.24 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (10030388..10038207, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (9960163..9967981, complement)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in developmental process	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: transcription factor 24

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001285425.2 → NP_001272354.1 transcription factor 24

See identical proteins and their annotated locations for NP_001272354.1

Status: VALIDATED

Source sequence(s)

AC102570

Consensus CDS

CCDS69862.1

UniProtKB/TrEMBL

V9GWT9

Conserved Domains (1) summary

cd19710
Location:49 → 104

bHLH_TS_TCF24; basic helix-loop-helix (bHLH) domain found in transcription factor 24 (TCF-24) and similar proteins