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Mup12 major urinary protein 12 [ Mus musculus (house mouse) ]

Gene ID: 100039054, updated on 17-Aug-2024

Summary

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Official Symbol
Mup12provided by MGI
Official Full Name
major urinary protein 12provided by MGI
Primary source
MGI:MGI:3780193
See related
Ensembl:ENSMUSG00000094793 AllianceGenome:MGI:3780193
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mup1; Gm2024
Summary
Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward liver adult (RPKM 2138.8) See more
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Genomic context

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See Mup12 in Genome Data Viewer
Location:
4 B3; 4 32.86 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (60693360..60697415, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (60737381..60741416, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene major urinary protein 11 Neighboring gene major urinary protein, pseudogene 7 Neighboring gene major urinary protein, pseudogene 8 Neighboring gene major urinary protein 22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Components of major urinary proteins (MUP's) in the mouse. Sex, strain, and subspecies differences. Hayakawa J, et al. J Hered, 1983 Nov-Dec. PMID 6643987
  2. Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice. Hui X, et al. J Biol Chem, 2009 May 22. PMID 19336396, Free PMC Article
  3. Identification of MUP1 as a regulator for glucose and lipid metabolism in mice. Zhou Y, et al. J Biol Chem, 2009 Apr 24. PMID 19258313, Free PMC Article
  4. Structural basis of pheromone binding to mouse major urinary protein (MUP-I). Timm DE, et al. Protein Sci, 2001 May. PMID 11316880, Free PMC Article
  5. Mapping the structural genes coding for the major urinary proteins in the mouse: combined use of recombinant inbred strains and somatic cell hybrids. Bennett KL, et al. Proc Natl Acad Sci U S A, 1982 Feb. PMID 6951169, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
major urinary protein 12
Names
MUP 1
Major urinary protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199995.1 → NP_001186924.1  major urinary protein 12 precursor

    See identical proteins and their annotated locations for NP_001186924.1

    Status: VALIDATED

    Source sequence(s)
    CU062621
    Consensus CDS
    CCDS51192.1
    UniProtKB/Swiss-Prot
    P11588, P11589, Q61921, Q99JF6
    UniProtKB/TrEMBL
    B5TE76, B5X0G0, Q58ES8
    Related
    ENSMUSP00000112787.2, ENSMUST00000117932.2
    Conserved Domains (1) summary
    pfam00061
    Location:34 → 170
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    60693360..60697415 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537484.4 → XP_006537547.1  major urinary protein 12 isoform X1

    Conserved Domains (1) summary
    cd19428
    Location:23 → 172
    lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins
Nucleotide Protein
Heading Accession and Version

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