TNFSF13B TNF superfamily member 13b [Sus scrofa (pig)] - Gene

Summary

Official Symbol: TNFSF13Bprovided by VGNC
Official Full Name: TNF superfamily member 13bprovided by VGNC
Primary source: VGNC:VGNC:94269
See related: Ensembl:ENSSSCG00000009542
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as: BAFF
Expression: Broad expression in lung (RPKM 8.4), spleen (RPKM 8.3) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	11	NC_010453.5 (75599296..75633044)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	11	NC_010453.4 (83014191..83048071)

Chromosome 11 - NC_010453.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

This study demonstrated expression of BAFF on cultured monocyte-derived dendritic cells, which was further enhanced by interferon-alpha or interferon-gamma treatment.
Title: Porcine B-cell activating factor promotes anti-FMDV antibodies in vitro but not in vivo after DNA vaccination of pigs.
study reports the molecular cloning, expression and bioactivity of the porcine homologue of human BAFF
Title: cDNA cloning, expression and bioactivity of porcine BAFF.

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General gene information

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Markers

Abhd13 (e-PCR), detects polymorphism
- UniSTS:496706

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables receptor ligand activity	IEA Inferred from Electronic Annotation more info	PubMed
enables tumor necrosis factor receptor binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: tumor necrosis factor ligand superfamily member 13B

Names: B-cell activating factor; tumor necrosis factor superfamily member 13b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001097498.1 → NP_001090967.1 tumor necrosis factor ligand superfamily member 13B

See identical proteins and their annotated locations for NP_001090967.1

Status: PROVISIONAL

Source sequence(s)

EF041845

UniProtKB/TrEMBL

A0A4X1U7N3, A0A8D0S803, A0MTC9, A9CDZ0

Related

ENSSSCP00000010188.1, ENSSSCT00000010460.3

Conserved Domains (1) summary

cd00184
Location:94 → 230

TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

NC_010453.5 Reference Sscrofa11.1 Primary Assembly

Range

75599296..75633044

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005668532.3 → XP_005668589.1 tumor necrosis factor ligand superfamily member 13B isoform X3

Conserved Domains (1) summary

cl00147
Location:142 → 194

TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
XM_005668531.3 → XP_005668588.1 tumor necrosis factor ligand superfamily member 13B isoform X2

UniProtKB/TrEMBL

A0A8D0V7R3

Conserved Domains (1) summary

cd00184
Location:136 → 259

TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
XM_005668530.3 → XP_005668587.1 tumor necrosis factor ligand superfamily member 13B isoform X1

UniProtKB/TrEMBL

A0A480ZL10, A0A8D1TQZ4, A9CDZ0

Conserved Domains (1) summary

cd00184
Location:142 → 278

TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...