hsp70 heat shock 70kDa protein [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: hsp70provided by Xenbase
Official Full Name: heat shock 70kDa proteinprovided by Xenbase
Primary source: Xenbase:XB-GENE-485626
See related: AllianceGenome:Xenbase:XB-GENE-485626
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: xhsp70
Summary: Predicted to enable ATP binding activity and ATP-dependent protein folding chaperone. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to several human genes including HSPA1L (heat shock protein family A (Hsp70) member 1 like) and HSPA1B (heat shock protein family A (Hsp70) member 1B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	8	NC_030684.2 (75108296..75111281)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	8	NC_030684.1 (52782710..52785650, complement)

Chromosome 8 - NC_030684.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ATP-dependent protein folding chaperone	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: heat shock 70kDa protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001112899.1 → NP_001106370.1 heat shock 70kDa protein

See identical proteins and their annotated locations for NP_001106370.1

Status: PROVISIONAL

Source sequence(s)

BC155367

UniProtKB/TrEMBL

A0A803JLU6, A9JTJ5

Conserved Domains (2) summary

cd10233
Location:7 → 382

HSPA1-2_6-8-like_NBD; Nucleotide-binding domain of HSPA1-A, -B, -L, HSPA-2, -6, -7, -8, and similar proteins

PTZ00009
Location:2 → 643

PTZ00009; heat shock 70 kDa protein; Provisional