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cdnf cerebral dopamine neurotrophic factor [ Danio rerio (zebrafish) ]

Gene ID: 100037317, updated on 27-Mar-2024

Summary

Official Symbol
cdnfprovided by ZNC
Official Full Name
cerebral dopamine neurotrophic factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070410-37
See related
Ensembl:ENSDARG00000075501 AllianceGenome:ZFIN:ZDB-GENE-070410-37
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:162209
Summary
Predicted to enable growth factor activity. Predicted to be involved in dopaminergic neuron differentiation and neuron projection development. Predicted to be located in extracellular region. Predicted to be active in endoplasmic reticulum and extracellular space. Orthologous to human CDNF (cerebral dopamine neurotrophic factor). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See cdnf in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (9587968..9592402, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (9587052..9591486, complement)

Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene thymidine phosphorylase Neighboring gene SH3 and multiple ankyrin repeat domains 3b Neighboring gene heat shock protein 14 Neighboring gene DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae) Neighboring gene meiosis/spermiogenesis associated 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in dopaminergic neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in neuron projection development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of dopaminergic neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
cerebral dopamine neurotrophic factor
Names
arginine-rich, mutated in early stage tumors-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123281.1NP_001116753.1  cerebral dopamine neurotrophic factor precursor

    See identical proteins and their annotated locations for NP_001116753.1

    Status: PROVISIONAL

    Source sequence(s)
    BX901962
    UniProtKB/TrEMBL
    A0A8N1Z028, A4QNW4
    Related
    ENSDARP00000100729.3, ENSDART00000114060.4
    Conserved Domains (1) summary
    pfam10208
    Location:27172
    Armet; Degradation arginine-rich protein for mis-folding

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007115.7 Reference GRCz11 Primary Assembly

    Range
    9587968..9592402 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394550.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    139422..143853 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395230.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    11930..16364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)