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rps6ka4.L ribosomal protein S6 kinase, 90kDa, polypeptide 4 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100037253, updated on 4-Nov-2024

Summary

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Official Symbol
rps6ka4.L
Official Full Name
ribosomal protein S6 kinase, 90kDa, polypeptide 4 L homeolog
Primary source
Xenbase:XB-GENE-5759520
Locus tag
XELAEV_18022245mg
See related
EnsemblRapid:ENSXLAG00005019766 AllianceGenome:Xenbase:XB-GENE-5759520
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rps6ka4
Summary
Predicted to enable ATP binding activity; histone H2AS1 kinase activity; and magnesium ion binding activity. Predicted to act upstream of or within intracellular signal transduction; peptidyl-serine phosphorylation; and regulation of DNA-templated transcription. Orthologous to human RPS6KA4 (ribosomal protein S6 kinase A4). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rps6ka4.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (27725190..27758659, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (26205234..26239029, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene WD repeat domain 74 L homeolog Neighboring gene solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog Neighboring gene AHNAK nucleoprotein L homeolog Neighboring gene uncharacterized LOC108713920

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables histone H2AS1 kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal protein S6 kinase, 90kDa, polypeptide 4 L homeolog
Names
ribosomal protein S6 kinase, polypeptide 4
NP_001091395.1
XP_018111814.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097926.1 → NP_001091395.1  ribosomal protein S6 kinase, 90kDa, polypeptide 4 L homeolog

    See identical proteins and their annotated locations for NP_001091395.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124881
    UniProtKB/TrEMBL
    A0A974HNH8, A0AUT3
    Related
    ENSXLAP00005058079.1, ENSXLAT00005059436.1
    Conserved Domains (3) summary
    smart00220
    Location:29 → 294
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd05614
    Location:28 → 357
    STKc_MSK2_N; N-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 2
    cd14180
    Location:394 → 701
    STKc_MSK2_C; C-terminal catalytic domain of the Serine/Threonine Kinase, Mitogen and stress-activated kinase 2

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    27725190..27758659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018256325.2 → XP_018111814.1  ribosomal protein S6 kinase, 90kDa, polypeptide 4 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J0UYC8
    Related
    ENSXLAP00005058088.1, ENSXLAT00005059445.1
Nucleotide Protein Strain
Heading Accession and Version

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