ppt1.L palmitoyl-protein thioesterase 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ppt1.L
Official Full Name: palmitoyl-protein thioesterase 1 L homeolog
Primary source: Xenbase:XB-GENE-6254984
Locus tag: XELAEV_18012631mg
See related: EnsemblRapid:ENSXLAG00005002996 AllianceGenome:Xenbase:XB-GENE-6254984
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ppt1
Summary: Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to act upstream of or within protein depalmitoylation and receptor-mediated endocytosis. Predicted to be located in lysosome. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2L

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2L	NC_054373.1 (94485586..94496610)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2L	NC_030726.1 (88735052..88746437)

Chromosome 2L - NC_054373.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables palmitoyl hydrolase activity	IEA Inferred from Electronic Annotation more info
enables palmitoyl-(protein) hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein depalmitoylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within receptor-mediated endocytosis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in lysosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: palmitoyl-protein thioesterase 1 L homeolog

NP_001091368.1

EC 3.1.2.22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.