U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cst7.L cystatin F L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100037093, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
cst7.L
Official Full Name
cystatin F L homeolog
Primary source
Xenbase:XB-GENE-6255508
Locus tag
XELAEV_18026573mg
See related
EnsemblRapid:ENSXLAG00005012730 AllianceGenome:Xenbase:XB-GENE-6255508
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cst7
Summary
Predicted to enable cysteine-type endopeptidase inhibitor activity. Predicted to act upstream of or within several processes, including inhibition of cysteine-type endopeptidase activity; negative regulation of microglial cell activation; and positive regulation of myelination. Predicted to be located in several cellular components, including Golgi apparatus; late endosome; and lysosome. Orthologous to human CST7 (cystatin F). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cst7.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (37072268..37086019, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (36341943..36353936, complement)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene cystatin-C Neighboring gene synapse differentiation inducing 1 L homeolog Neighboring gene adipocyte plasma membrane associated protein L homeolog Neighboring gene ectonucleoside triphosphate diphosphohydrolase 6 (putative) L homeolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cysteine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within immune response IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within inhibition of cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of microglial cell activation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of myelination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in late endosome IEA
Inferred from Electronic Annotation
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
cystatin F L homeolog
Names
cystatin F (leukocystatin)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097812.1 → NP_001091281.1  cystatin F L homeolog precursor

    See identical proteins and their annotated locations for NP_001091281.1

    Status: PROVISIONAL

    Source sequence(s)
    BC130168
    UniProtKB/TrEMBL
    A0A974CU02, A2BDB8
    Related
    ENSXLAP00005037435.1, ENSXLAT00005038344.1
    Conserved Domains (1) summary
    smart00043
    Location:34 → 143
    CY; Cystatin-like domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    37072268..37086019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562019.1 → XP_041417953.1  cystatin F L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1KMJ9, A0A974CU02
    Conserved Domains (1) summary
    smart00043
    Location:35 → 114
    CY; Cystatin-like domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.