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insig1.S insulin induced gene 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100036994, updated on 4-Nov-2024

Summary

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Official Symbol
insig1.S
Official Full Name
insulin induced gene 1 S homeolog
Primary source
Xenbase:XB-GENE-17330164
Locus tag
XELAEV_18032825mg
See related
EnsemblRapid:ENSXLAG00005032287 AllianceGenome:Xenbase:XB-GENE-17330164
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cl6; cl-6
Summary
Predicted to act upstream of or within several processes, including SREBP signaling pathway; SREBP-SCAP complex retention in endoplasmic reticulum; and cellular response to insulin stimulus. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of SREBP-SCAP-Insig complex. Orthologous to human INSIG1 (insulin induced gene 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See insig1.S in Genome Data Viewer
Location:
chromosome: 6S
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 6S NC_054382.1 (10780362..10791157)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 6S NC_030735.1 (10401520..10412307)

Chromosome 6S - NC_054382.1Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled S homeolog Neighboring gene uncharacterized LOC121395225 Neighboring gene engrailed homeobox 2 S homeolog Neighboring gene canopy FGF signaling regulator 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within SREBP signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within SREBP-SCAP complex retention in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cholesterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SREBP-SCAP-Insig complex IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Insulin-induced gene 1 protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097750.1 → NP_001091219.1  Insulin-induced gene 1 protein-like

    See identical proteins and their annotated locations for NP_001091219.1

    Status: PROVISIONAL

    Source sequence(s)
    BC130074
    UniProtKB/TrEMBL
    A0A974HDU0, A1L3F8
    Related
    ENSXLAP00005096807.1, ENSXLAT00005098587.1
    Conserved Domains (1) summary
    pfam07281
    Location:58 → 238
    INSIG; Insulin-induced protein (INSIG)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054382.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    10780362..10791157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials