zbtb8a.S zinc finger and BTB domain containing 8A, gene 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: zbtb8a.S
Official Full Name: zinc finger and BTB domain containing 8A, gene 1 S homeolog
Primary source: Xenbase:XB-GENE-6255849
Locus tag: XELAEV_18004047mg
See related: EnsemblRapid:ENSXLAG00005003368 AllianceGenome:Xenbase:XB-GENE-6255849
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: bozf1; zbtb8; zbtb8.1; zbtb8a-b; zbtb8a.1; zbtb8a.1-a; zbtb8a.1-b; zbtb8a.1.S
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and metal ion binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZBTB8A (zinc finger and BTB domain containing 8A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2S

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2S	NC_054374.1 (82215264..82230496, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016694858.1 (138333..157223, complement)

Chromosome 2S - NC_054374.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger and BTB domain-containing protein 8A.1-B

Names: zinc finger and BTB domain-containing protein 8A-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001097724.1 → NP_001091193.1 zinc finger and BTB domain-containing protein 8A.1-B

See identical proteins and their annotated locations for NP_001091193.1

Status: PROVISIONAL

Source sequence(s)

BC129718

UniProtKB/Swiss-Prot

A1L2U9

UniProtKB/TrEMBL

A0A974BRU9

Conserved Domains (5) summary

smart00225
Location:25 → 122

BTB; Broad-Complex, Tramtrack and Bric a brac

COG5048
Location:315 → 368

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:317 → 337

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00651
Location:14 → 119

BTB; BTB/POZ domain

pfam13465
Location:329 → 354

zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

82215264..82230496 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041582912.1 → XP_041438846.1 zinc finger and BTB domain-containing protein 8A.1-B isoform X1

UniProtKB/TrEMBL

A0A8J1MBW3, A0A974BRU9

Related

ENSXLAP00005010022.1, ENSXLAT00005010181.1

Conserved Domains (3) summary

COG5048
Location:334 → 387

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:336 → 356

ZF_C2H2; C2H2 Zn finger [structural motif]

cd18329
Location:22 → 137

BTB_POZ_ZBTB8A_BOZF1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 8A (ZBTB8A)
XM_018241744.2 → XP_018097233.1 zinc finger and BTB domain-containing protein 8A.1-B isoform X2

UniProtKB/TrEMBL

A0A8J0U579, A0A974BRU9