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ctsh.L cathepsin H L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100036949, updated on 4-Nov-2024

Summary

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Official Symbol
ctsh.L
Official Full Name
cathepsin H L homeolog
Primary source
Xenbase:XB-GENE-5820439
Locus tag
XELAEV_18018109mg
See related
EnsemblRapid:ENSXLAG00005035285 AllianceGenome:Xenbase:XB-GENE-5820439
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ctsh
Summary
Predicted to enable cysteine-type endopeptidase activity. Predicted to act upstream of or within proteolysis involved in protein catabolic process. Predicted to be located in extracellular space; lysosome; and plasma membrane. Orthologous to human CTSH (cathepsin H). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ctsh.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (100699680..100711979, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (85394238..85406616, complement)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene ervatamin-C-like Neighboring gene cathepsin L L homeolog Neighboring gene proto-oncogene Mas Neighboring gene MAS1 proto-oncogene, G protein-coupled receptor L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables cysteine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cathepsin H
NP_001091187.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097718.1 → NP_001091187.1  cathepsin H

    See identical proteins and their annotated locations for NP_001091187.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129703
    UniProtKB/TrEMBL
    A0A974DCX5, A1L2T8
    Related
    ENSXLAP00005105521.1, ENSXLAT00005107574.1
    Conserved Domains (2) summary
    smart00848
    Location:14 → 73
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    cd02248
    Location:104 → 313
    Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    100699680..100711979 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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