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tuba8.S tubulin alpha 8 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100036943, updated on 4-Nov-2024

Summary

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Official Symbol
tuba8.S
Official Full Name
tubulin alpha 8 S homeolog
Primary source
Xenbase:XB-GENE-490059
Locus tag
XELAEV_18019849mg
See related
EnsemblRapid:ENSXLAG00005000736 AllianceGenome:Xenbase:XB-GENE-490059
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tuba1; tubal2
Summary
Predicted to enable GTP binding activity and hydrolase activity. Predicted to be a structural constituent of cytoskeleton. Predicted to act upstream of or within microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Is expressed in dermal system; endoderm; and nervous system. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to human TUBA8 (tubulin alpha 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tuba8.S in Genome Data Viewer
Location:
chromosome: 3S
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (5056976..5064562)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (5074066..5078111)

Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 19 S homeolog Neighboring gene uncharacterized LOC121402090 Neighboring gene ubiquitin specific peptidase 18 S homeolog Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 3 S homeolog Neighboring gene uncharacterized LOC121402091

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within microtubule-based process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tubulin alpha 8 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097713.1 → NP_001091182.1  tubulin alpha 8 S homeolog

    See identical proteins and their annotated locations for NP_001091182.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129696
    UniProtKB/TrEMBL
    A0A974D7L6, A1L2T2
    Related
    ENSXLAP00005002159.1, ENSXLAT00005002205.1
    Conserved Domains (2) summary
    PTZ00335
    Location:9 → 455
    PTZ00335; tubulin alpha chain; Provisional
    cd02186
    Location:9 → 442
    alpha_tubulin; The alpha-tubulin family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    5056976..5064562
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials