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lfng.L LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100036937, updated on 4-Nov-2024

Summary

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Official Symbol
lfng.L
Official Full Name
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase L homeolog
Primary source
Xenbase:XB-GENE-865754
Locus tag
XELAEV_18045227mg
See related
AllianceGenome:Xenbase:XB-GENE-865754
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
lfng
Summary
Predicted to enable O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity and metal ion binding activity. Predicted to act upstream of or within pattern specification process and regulation of Notch signaling pathway. Predicted to be located in Golgi membrane. Is expressed in anatomical system; pharyngeal arch; and primary germ layer. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 3. Orthologous to human LFNG (LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lfng.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
8
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (104584168..104594392, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (94042061..94052324, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene IQ motif containing E L homeolog Neighboring gene tweety family member 3 L homeolog Neighboring gene grifin-like Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within pattern specification process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase L homeolog
Names
lunatic fringe
NP_001091176.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097707.1 → NP_001091176.1  LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase L homeolog

    See identical proteins and their annotated locations for NP_001091176.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129688
    UniProtKB/TrEMBL
    A0A974H4H1, A1L2S5
    Conserved Domains (1) summary
    pfam02434
    Location:104 → 352
    Fringe; Fringe-like

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    104584168..104594392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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