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ap1ar.S adaptor related protein complex 1 associated regulatory protein S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100036917, updated on 4-Nov-2024

Summary

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Official Symbol
ap1ar.S
Official Full Name
adaptor related protein complex 1 associated regulatory protein S homeolog
Primary source
Xenbase:XB-GENE-5953419
Locus tag
XELAEV_18009353mg
See related
EnsemblRapid:ENSXLAG00005003599 AllianceGenome:Xenbase:XB-GENE-5953419
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ap1ar
Summary
Predicted to enable AP-1 adaptor complex binding activity and kinesin binding activity. Predicted to act upstream of or within several processes, including negative regulation of substrate adhesion-dependent cell spreading; regulation of Arp2/3 complex-mediated actin nucleation; and vesicle targeting, trans-Golgi to endosome. Predicted to be located in endosome. Orthologous to human AP1AR (adaptor related protein complex 1 associated regulatory protein). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ap1ar.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (57070869..57087620)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (56593138..56609990)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2 group XIIA S homeolog Neighboring gene uncharacterized LOC108706708 Neighboring gene TRAF-interacting protein with forkhead-associated domain S homeolog Neighboring gene neurogenin 2 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables AP-1 adaptor complex binding IEA
Inferred from Electronic Annotation
more info
  
enables kinesin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of cell motility IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of Arp2/3 complex-mediated actin nucleation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vesicle targeting, trans-Golgi to endosome IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
adaptor related protein complex 1 associated regulatory protein S homeolog
Names
adaptor-related protein complex 1 associated regulatory protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097691.1 → NP_001091160.1  adaptor related protein complex 1 associated regulatory protein S homeolog

    See identical proteins and their annotated locations for NP_001091160.1

    Status: PROVISIONAL

    Source sequence(s)
    BC129651
    UniProtKB/TrEMBL
    A1L2Q1, Q5EAY0
    Related
    ENSXLAP00005010739.1, ENSXLAT00005010907.1
    Conserved Domains (1) summary
    pfam15745
    Location:23 → 286
    AP1AR; AP-1 complex-associated regulatory protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    57070869..57087620
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041572116.1 → XP_041428050.1  adaptor related protein complex 1 associated regulatory protein S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1LH90

  2. XM_041572111.1 → XP_041428045.1  adaptor related protein complex 1 associated regulatory protein S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LH86, Q5EAY0

  3. XM_018231982.2 → XP_018087471.1  adaptor related protein complex 1 associated regulatory protein S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J0TPG3

  4. XM_018231974.2 → XP_018087463.1  adaptor related protein complex 1 associated regulatory protein S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A1L8HM01, A0A974I0R3, Q5EAY0
    Related
    ENSXLAP00005010743.1, ENSXLAT00005010911.1
Nucleotide Protein Strain
Heading Accession and Version

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