cd38.L CD38 molecule L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: cd38.L
Official Full Name: CD38 molecule L homeolog
Primary source: Xenbase:XB-GENE-945956
Locus tag: XELAEV_18005146mg
See related: EnsemblRapid:ENSXLAG00005001509 AllianceGenome:Xenbase:XB-GENE-945956
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: cd38
Summary: Predicted to enable hydrolase activity, hydrolyzing N-glycosyl compounds; phosphorus-oxygen lyase activity; and transferase activity. Predicted to act upstream of or within positive regulation of B cell proliferation. Predicted to be located in plasma membrane. Is expressed in mesoderm. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human CD38 (CD38 molecule). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1L

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1L	NC_054371.1 (29436952..29448736)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1L	NC_030724.1 (20665771..20677605)

Chromosome 1L - NC_054371.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

unknown role for CD38 as an essential regulator of embryonic development.
Title: The signaling protein CD38 is essential for early embryonic development.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables NAD+ nucleosidase activity	IEA Inferred from Electronic Annotation more info
enables NAD+ nucleotidase, cyclic ADP-ribose generating	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables phosphorus-oxygen lyase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of B cell proliferation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: CD38 molecule L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.