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kiaa0319l KIAA0319-like [ Danio rerio (zebrafish) ]

Gene ID: 100034533, updated on 2-Nov-2024

Summary

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Official Symbol
kiaa0319lprovided by ZNC
Official Full Name
KIAA0319-likeprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-110
See related
Ensembl:ENSDARG00000035660 AllianceGenome:ZFIN:ZDB-GENE-060503-110
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-193k19.1
Summary
Predicted to be involved in neuron migration. Predicted to be active in Golgi apparatus; cytoplasmic vesicle; and membrane. Is expressed in axis; brain; head; otic vesicle; and trunk. Orthologous to human KIAA0319L (KIAA0319 like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See kiaa0319l in Genome Data Viewer
Location:
chromosome: 19
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (43669329..43708078)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (44073534..44111664)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene si:ch211-199g17.9 Neighboring gene family with sequence similarity 83 member Hb Neighboring gene si:ch211-193k19.2 Neighboring gene CAP, adenylate cyclase-associated protein 1 (yeast) Neighboring gene si:ch1073-513e17.1 Neighboring gene palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The dyslexia susceptibility KIAA0319 gene shows a specific expression pattern during zebrafish development supporting a role beyond neuronal migration. Gostic M, et al. J Comp Neurol, 2019 Nov 1. PMID 30950042, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in neuron migration IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
KIAA0319-like; dyslexia-associated protein KIAA0319-like protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    43669329..43708078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003200638.6 → XP_003200686.2  dyslexia-associated protein KIAA0319-like protein homolog isoform X2

    UniProtKB/TrEMBL
    A0A8M1RTA0
    Related
    ENSDARP00000117936.2, ENSDART00000139151.4
    Conserved Domains (2) summary
    smart00089
    Location:307 → 393
    PKD; Repeats in polycystic kidney disease 1 (PKD1) and other proteins
    cd00146
    Location:401 → 489
    PKD; polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is ...

  2. XM_068215332.1 → XP_068071433.1  dyslexia-associated protein KIAA0319-like protein homolog isoform X1

Nucleotide Protein
Heading Accession and Version

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